{"id":634,"date":"2018-05-12T10:58:25","date_gmt":"2018-05-12T07:58:25","guid":{"rendered":"http:\/\/mde.biologia.gr\/koupa\/?p=634"},"modified":"2018-05-14T18:34:10","modified_gmt":"2018-05-14T15:34:10","slug":"%ce%b7-%cf%80%cf%81%cf%8e%cf%84%ce%b7-%ce%bc%ce%bf%cf%85-%ce%b5%ce%bc%cf%80%ce%b5%ce%b9%cf%81%ce%af%ce%b1-%cf%89%cf%82-%ce%b1%cf%81%ce%b8%cf%81%ce%bf%ce%b3%cf%81%ce%ac%cf%86%ce%bf%cf%85%cf%83","status":"publish","type":"post","link":"https:\/\/mde.biologia.gr\/koupa\/2018\/05\/12\/%ce%b7-%cf%80%cf%81%cf%8e%cf%84%ce%b7-%ce%bc%ce%bf%cf%85-%ce%b5%ce%bc%cf%80%ce%b5%ce%b9%cf%81%ce%af%ce%b1-%cf%89%cf%82-%ce%b1%cf%81%ce%b8%cf%81%ce%bf%ce%b3%cf%81%ce%ac%cf%86%ce%bf%cf%85%cf%83\/","title":{"rendered":"\u0397 \u03c0\u03c1\u03ce\u03c4\u03b7 \u03bc\u03bf\u03c5 \u03b5\u03bc\u03c0\u03b5\u03b9\u03c1\u03af\u03b1, \u03c9\u03c2 &#8220;\u03b1\u03c1\u03b8\u03c1\u03bf\u03b3\u03c1\u03ac\u03c6\u03bf\u03c5&#8221; \u03c4\u03b7\u03c2 \u0392\u03b9\u03ba\u03b9\u03c0\u03b1\u03af\u03b4\u03b5\u03b9\u03b1\u03c2"},"content":{"rendered":"<p>\u03a3\u03c4\u03b1 \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03b1 \u03c4\u03bf\u03c5 \u03bc\u03b1\u03b8\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 &#8220;\u0395\u03ba\u03c0\u03b1\u03b9\u03b4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03a4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1- \u03a0\u03bf\u03bb\u03c5\u03bc\u03ad\u03c3\u03b1 \u03c3\u03c4\u03b7 \u0394\u03b9\u03b4\u03b1\u03c3\u03ba\u03b1\u03bb\u03af\u03b1 \u03c4\u03b7\u03c2 \u0392\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2\u00a0 \u00a0\u03c4\u03bf\u03c5 \u03bc\u03b5\u03c4\u03b1\u03c0\u03c4\u03c5\u03c7\u03b9\u03b1\u03ba\u03bf\u03cd \u03c0\u03c1\u03bf\u03b3\u03c1\u03ac\u03bc\u03bc\u03b1\u03c4\u03bf\u03c2 \u00a8\u0394\u03b9\u03b4\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03c4\u03b7\u03c2 \u0392\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2&#8221;, \u03ba\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03ba\u03b1\u03b8\u03bf\u03b4\u03ae\u03b3\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u0394\u03ac\u03c3\u03ba\u03b1\u03bb\u03bf\u03c5 (\u039caster of the Universe) \u03a0. \u03a3\u03c4\u03b1\u03c3\u03b9\u03bd\u03ac\u03ba\u03b7, \u03ad\u03c6\u03c4\u03b9\u03b1\u03be\u03b1 \u03ba\u03b1\u03b9 \u03b3\u03c9 \u03bc\u03b9\u03b1 &#8220;\u03c4\u03b1\u03c0\u03b5\u03b9\u03bd\u03ae \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03b1\u03c6\u03c1\u03bf\u03bd\u03b5\u03bc\u03ad\u03bd\u03b7&#8221; \u03c3\u03b5\u03bb\u03af\u03b4\u03b1 \u03c3\u03c4\u03b7 \u0392\u03b9\u03ba\u03b9\u03c0\u03b1\u03af\u03b4\u03b5\u03b9\u03b1, \u03b5\u03bd\u03ce \u03c0\u03b1\u03c1\u03ac\u03bb\u03bb\u03b7\u03bb\u03b1 \u03ad\u03ba\u03b1\u03bd\u03b1 \u03ba\u03b1\u03b9 \u03bc\u03af\u03b1 \u03c0\u03c1\u03bf\u03c3\u03b8\u03ae\u03ba\u03b7 \u03c3\u03b5 \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03bd \u03ac\u03c1\u03b8\u03c1\u03bf \u03c4\u03b7\u03c2 \u0392\u03b9\u03ba\u03b9\u03c0\u03b1\u03af\u03b4\u03b5\u03b9\u03b1\u03c2. \u039c\u03bf\u03c5 \u03ac\u03c1\u03b5\u03c3\u03b5 \u03cc\u03bc\u03c9\u03c2 \u03c4\u03cc\u03c3\u03bf \u03c0\u03bf\u03bb\u03cd, \u03c0\u03bf\u03c5 \u03c3\u03c4\u03b7\u03bd \u03ba\u03c5\u03c1\u03b9\u03bf\u03bb\u03b5\u03be\u03af\u03b1 \u03b2\u03bf\u03bc\u03b2\u03ac\u03c1\u03b4\u03b9\u03c3\u03b1 \u03c4\u03bf \u0394\u03ac\u03c3\u03ba\u03b1\u03bb\u03bf \u03bc\u03b5 \u03bc\u03b7\u03bd\u03cd\u03bc\u03b1\u03c4\u03b1, \u03c0\u03c1\u03bf\u03ba\u03b5\u03b9\u03bc\u03ad\u03bd\u03bf\u03c5 \u03bd\u03b1 \u03c4\u03bf\u03bd \u03b5\u03bd\u03b7\u03bc\u03b5\u03c1\u03ce\u03c3\u03c9 \u03b3\u03b9\u03b1 \u03c4\u03bf \u03b5\u03c0\u03af\u03c4\u03b5\u03c5\u03b3\u03bc\u03ac \u03bc\u03bf\u03c5 &#8221; \u03ad\u03ba\u03b1\u03bd\u03b1 \u03b1\u03c5\u03c4\u03cc, \u03ad\u03ba\u03b1\u03bd\u03b1 \u03b5\u03ba\u03b5\u03af\u03bd\u03bf, \u03ad\u03b2\u03b1\u03bb\u03b1 \u03ba\u03b1\u03b9 \u03b1\u03c5\u03c4\u03cc &#8230;&#8221; \u03ba\u03b1\u03b9 \u03c3\u03b9\u03b3\u03ac \u03c4\u03b1 \u03c9\u03ac&#8230; \u03b8\u03b1 \u03c0\u03b5\u03b9 \u03ba\u03ac\u03c0\u03bf\u03b9\u03bf\u03c2. \u039a\u03b9 \u03cc\u03bc\u03c9\u03c2, \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03cc\u03c3\u03bf \u03ad\u03bd\u03c4\u03bf\u03bd\u03b7 \u03b7 \u03b1\u03af\u03c3\u03b8\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b4\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03c3\u03c5\u03bd\u03b5\u03b9\u03c3\u03c6\u03bf\u03c1\u03ac\u03c2 \u03c3\u03b5 \u03ad\u03bd\u03b1 &#8220;\u03b9\u03bd\u03c4\u03b5\u03c1\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc\u00a0 \u03ba\u03bf\u03bb\u03bf\u03c3\u03c3\u03cc&#8221; , \u03c0\u03bf\u03c5 \u03b4\u03b5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af, \u03c0\u03b1\u03c1\u03ac \u03bd\u03b1 \u03c3\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c3\u03b4\u03ce\u03c3\u03b5\u03b9 \u03c3\u03c5\u03bd\u03b1\u03b9\u03c3\u03b8\u03ae\u03bc\u03b1\u03c4\u03b1 \u03b5\u03bd\u03b8\u03bf\u03c5\u03c3\u03b9\u03b1\u03c3\u03bc\u03bf\u03cd. \u0391\u03c6\u03bf\u03cd \u03bb\u03bf\u03b9\u03c0\u03cc\u03bd \u03c3\u03c4\u03b7 \u03b4\u03b9\u03ba\u03ae \u03bc\u03bf\u03c5 \u03c3\u03b5\u03bb\u03af\u03b4\u03b1, \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b8\u03b7\u03ba\u03b1 \u03c3\u03c4\u03b7 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03a4\u03a0\u0395 \u03c3\u03c4\u03b7\u03bd \u03b5\u03ba\u03c0\u03b1\u03af\u03b4\u03b5\u03c5\u03c3\u03b7, \u03ad\u03ba\u03b1\u03bd\u03b1 \u03ba\u03b1\u03b9 \u03bc\u03af\u03b1 \u03c0\u03c1\u03bf\u03c3\u03b8\u03ae\u03ba\u03b7 \u03c3\u03b5 \u03ad\u03bd\u03b1 \u03ac\u03c1\u03b8\u03c1\u03bf \u03bc\u03b5 \u03c4\u03af\u03c4\u03bb\u03bf &#8221; \u039f \u03c1\u03cc\u03bb\u03bf\u03c2 \u03c4\u03c9\u03bd \u03b4\u03cd\u03bf \u03c6\u03cd\u03bb\u03c9\u03bd&#8221;.\u00a0 \u03a3\u03ba\u03ad\u03c6\u03c4\u03b7\u03ba\u03b1 \u03cc\u03bc\u03c9\u03c2 \u03bc\u03b5\u03c4\u03ac \u03bd\u03b1 \u03c0\u03b5\u03b9\u03c1\u03b1\u03bc\u03b1\u03c4\u03b9\u03c3\u03c4\u03ce \u03ba\u03b1\u03b9 \u03bb\u03af\u03b3\u03bf \u03c0\u03b1\u03c1\u03b1\u03c0\u03ac\u03bd\u03c9, \u03bf\u03c0\u03cc\u03c4\u03b5 \u03b5\u03bd\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03c3\u03b1 \u03ba\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03b4\u03b9\u03ba\u03cc \u03bc\u03bf\u03c5 \u03bb\u03ae\u03bc\u03bc\u03b1, \u03b3\u03b9\u03b1 \u03c4\u03b9\u03c2 <strong>\u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2<\/strong>&#8211; \u03c0\u03c1\u03c9\u03c4\u03b5\u03ac\u03c3\u03b5\u03c2 \u03bc\u03b5 \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc \u03c1\u03cc\u03bb\u03bf \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1 \u03c4\u03b7\u03c2 \u03b1\u03c0\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7\u03c2-\u00a0 \u03c0\u03bf\u03c5 \u03bc\u03ad\u03c7\u03c1\u03b9 \u03c4\u03ce\u03c1\u03b1 \u03b4\u03b5\u03bd \u03c5\u03c0\u03cd\u03c1\u03c7\u03b5 \u03c3\u03c4\u03b7 \u0392\u03b9\u03ba\u03b9\u03c0\u03b1\u03af\u03b4\u03b5\u03b9\u03b1. \u03a3\u03b1\u03c2 \u03c0\u03b1\u03c1\u03b1\u03b8\u03ad\u03c4\u03c9 \u03c4\u03b1 <strong>\u03ba\u03b1\u03c4\u03bf\u03c1\u03b8\u03ce\u03bc\u03b1\u03c4\u03ac <\/strong>\u03bc\u03bf\u03c5, \u03c0\u03c1\u03bf\u03c2 \u03c4\u03ad\u03c1\u03c8\u03b7 \u03bf\u03c6\u03b8\u03b1\u03bb\u03bc\u03ce\u03bd:<\/p>\n<h3 id=\"firstHeading\" class=\"firstHeading\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%A7%CF%81%CE%AE%CF%83%CF%84%CE%B7%CF%82:Kpavlina70\">\u03a7\u03c1\u03ae\u03c3\u03c4\u03b7\u03c2:Kpavlina70<\/a><\/h3>\n<div id=\"bodyContent\" class=\"mw-body-content\">\n<div id=\"mw-content-text\" class=\"mw-content-ltr\" dir=\"ltr\" lang=\"el\">\n<div class=\"mw-parser-output\">\n<p>\u0393\u03b5\u03bd\u03bd\u03ae\u03b8\u03b7\u03ba\u03b1 \u03c3\u03c4\u03b7 \u039c\u03b1\u03ba\u03b5\u03b4\u03bf\u03bd\u03af\u03b1 \u03bc\u03b1\u03c2, \u03c3\u03c4\u03b7\u03bd \u03c0\u03b1\u03bd\u03ad\u03bc\u03bf\u03c1\u03c6\u03b7 \u03c0\u03cc\u03bb\u03b7 \u03c4\u03b7\u03c2 \u0398\u03b5\u03c3\u03c3\u03b1\u03bb\u03bf\u03bd\u03af\u03ba\u03b7\u03c2. \u03a4\u03b5\u03bb\u03b5\u03af\u03c9\u03c3\u03b1 \u03c4\u03b7 \u0393\u03b5\u03c9\u03c0\u03bf\u03bd\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03ac \u03c4\u03bf \u0392\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc, \u03b5\u03bd\u03ce \u03c4\u03b7 \u03c0\u03b5\u03c1\u03af\u03bf\u03b4\u03bf \u03b1\u03c5\u03c4\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03ce \u03ad\u03bd\u03b1 \u03bc\u03b5\u03c4\u03b1\u03c0\u03c4\u03c5\u03c7\u03b9\u03b1\u03ba\u03cc, \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b4\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03c4\u03b7\u03c2 \u0392\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2. \u0394\u03b9\u03b4\u03ac\u03c3\u03ba\u03c9 \u03c9\u03c2 \u03bc\u03cc\u03bd\u03b9\u03bc\u03b7 \u03b5\u03ba\u03c0\u03b1\u03b9\u03b4\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc\u03c2, \u03c3\u03b5 \u039b\u03cd\u03ba\u03b5\u03b9\u03bf \u03c4\u03bf\u03c5 \u0391\u03bc\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03bf\u03c5.<\/p>\n<p><span id=\"\u0392\u03bf\u03b7\u03b8\u03bf\u03cd\u03bd_\u03bf\u03b9_\u03a4\u03a0\u0395_\u03c3\u03c4\u03b7_\u03b4\u03b9\u03b4\u03b1\u03c3\u03ba\u03b1\u03bb\u03af\u03b1_\u03c4\u03b7\u03c2_\u0392\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2;\" class=\"mw-headline\"><b>\u0392\u03bf\u03b7\u03b8\u03bf\u03cd\u03bd \u03bf\u03b9 \u03a4\u03a0\u0395 \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b4\u03b1\u03c3\u03ba\u03b1\u03bb\u03af\u03b1 \u03c4\u03b7\u03c2 \u0392\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2;<\/b><\/span><span class=\"mw-editsection\" style=\"color: #00ccff\"><span class=\"mw-editsection-bracket\">[<\/span><a class=\"mw-editsection-visualeditor\" style=\"color: #00ccff\" title=\"\u0395\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03b5\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2: \u0392\u03bf\u03b7\u03b8\u03bf\u03cd\u03bd \u03bf\u03b9 \u03a4\u03a0\u0395 \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b4\u03b1\u03c3\u03ba\u03b1\u03bb\u03af\u03b1 \u03c4\u03b7\u03c2 \u0392\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2;\" href=\"https:\/\/el.wikipedia.org\/w\/index.php?title=%CE%A7%CF%81%CE%AE%CF%83%CF%84%CE%B7%CF%82:Kpavlina70&amp;veaction=edit&amp;section=1\">\u0395\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1<\/a><span class=\"mw-editsection-divider\">\u00a0|\u00a0<\/span><a style=\"color: #00ccff\" title=\"\u0395\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03b5\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2: \u0392\u03bf\u03b7\u03b8\u03bf\u03cd\u03bd \u03bf\u03b9 \u03a4\u03a0\u0395 \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b4\u03b1\u03c3\u03ba\u03b1\u03bb\u03af\u03b1 \u03c4\u03b7\u03c2 \u0392\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2;\" href=\"https:\/\/el.wikipedia.org\/w\/index.php?title=%CE%A7%CF%81%CE%AE%CF%83%CF%84%CE%B7%CF%82:Kpavlina70&amp;action=edit&amp;section=1\">\u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03ba\u03ce\u03b4\u03b9\u03ba\u03b1<\/a><span class=\"mw-editsection-bracket\">]<\/span><\/span><\/p>\n<div class=\"thumbinner\">\n<p><a class=\"image\" href=\"https:\/\/commons.wikimedia.org\/wiki\/File:E-book.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"thumbimage aligncenter\" src=\"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/7\/7f\/E-book.jpg\/220px-E-book.jpg\" alt=\"\" width=\"220\" height=\"142\" \/><\/a><\/p>\n<div class=\"thumbcaption\">\n<p style=\"text-align: center\">\u03a4\u03a0\u0395 \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b4\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae<\/p>\n<\/div>\n<\/div>\n<p><span 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\u03c4\u03bf\u03c5\u00a0<a title=\"\u039f\u03b9\u03ba\u03bf\u03b4\u03bf\u03bc\u03b9\u03c3\u03bc\u03cc\u03c2 (\u03c0\u03b1\u03b9\u03b4\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae)\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9F%CE%B9%CE%BA%CE%BF%CE%B4%CE%BF%CE%BC%CE%B9%CF%83%CE%BC%CF%8C%CF%82_(%CF%80%CE%B1%CE%B9%CE%B4%CE%B1%CE%B3%CF%89%CE%B3%CE%B9%CE%BA%CE%AE)\"><b>\u03b5\u03c0\u03bf\u03b9\u03ba\u03bf\u03b4\u03bf\u00b5\u03b9\u03c3\u00b5\u03bf\u03cd<\/b><\/a>.&#8221;<\/p>\n<p>\u0395\u03bc\u03ad\u03bd\u03b1 \u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b9\u03ba\u03ac \u03b7 \u03c4\u03bf\u03c0\u03bf\u03b8\u03ad\u03c4\u03b7\u03c3\u03b7 \u03b1\u03c5\u03c4\u03ae \u03bc\u03b5 \u03b2\u03c1\u03af\u03c3\u03ba\u03b5\u03b9 \u03b1\u03c0\u03cc\u03bb\u03c5\u03c4\u03b1 \u03c3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b7.\u03a5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03ba\u03ac\u03c0\u03bf\u03b9\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03b4\u03b9\u03b1\u03c6\u03c9\u03bd\u03b5\u03af; \u03a7\u03c9\u03c1\u03af\u03c2 \u03bd\u03b1 \u03b9\u03c3\u03c7\u03c5\u03c1\u03af\u03b6\u03bf\u03bc\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c4\u03c9\u03bd \u03a4\u03a0\u0395 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b1\u03bd\u03ac\u03ba\u03b5\u03b9\u03b1, \u03c0\u03c1\u03bf\u03c4\u03b5\u03af\u03bd\u03c9: \u0391\u03c2 \u03c4\u03bf \u03be\u03b5\u03bd\u03b1\u03c3\u03ba\u03b5\u03c6\u03b8\u03bf\u03cd\u03bc\u03b5&#8230;<\/p>\n<\/div>\n<p><span style=\"color: #ff0000\"><strong>\u03ba\u03b1\u03b9 \u03b7 \u03c0\u03c1\u03bf\u03c3\u03b8\u03ae\u03ba\u03b7 \u03c0\u03bf\u03c5 \u03ad\u03ba\u03b1\u03bd\u03b1 \u03c3\u03c4\u03bf \u03bb\u03ae\u03bc\u03bc\u03b1 \u03bc\u03b5 \u03c4\u03af\u03c4\u03bb\u03bf <span style=\"color: #3366ff\"><a style=\"color: #3366ff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%A1%CF%8C%CE%BB%CE%BF%CF%82_%CF%86%CF%8D%CE%BB%CE%BF%CF%85\">&#8220;\u03a1\u03cc\u03bb\u03bf\u03c2 \u03c6\u03cd\u03bb\u03bf\u03c5&#8221;<\/a><\/span><\/strong><\/span><\/p>\n<h5><span id=\"\u0392\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\" class=\"mw-headline\">\u0392\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1<\/span><span class=\"mw-editsection\" style=\"color: #00ccff\"><span class=\"mw-editsection-bracket\">[<\/span><a class=\"mw-editsection-visualeditor\" style=\"color: #00ccff\" title=\"\u0395\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03b5\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2: \u0392\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\" href=\"https:\/\/el.wikipedia.org\/w\/index.php?title=%CE%A1%CF%8C%CE%BB%CE%BF%CF%82_%CF%86%CF%8D%CE%BB%CE%BF%CF%85&amp;veaction=edit&amp;section=4\">\u0395\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1<\/a><span class=\"mw-editsection-divider\">\u00a0|\u00a0<\/span><a style=\"color: #00ccff\" title=\"\u0395\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03b5\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2: \u0392\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\" href=\"https:\/\/el.wikipedia.org\/w\/index.php?title=%CE%A1%CF%8C%CE%BB%CE%BF%CF%82_%CF%86%CF%8D%CE%BB%CE%BF%CF%85&amp;action=edit&amp;section=4\">\u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03ba\u03ce\u03b4\u03b9\u03ba\u03b1<\/a><span class=\"mw-editsection-bracket\">]<\/span><\/span><\/h5>\n<p>\u0395\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03ad\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf \u03bd\u03bf\u03c1\u03b2\u03b7\u03b3\u03b9\u03ba\u03cc \u03c0\u03b1\u03bd\u03b5\u03c0\u03b9\u03c3\u03c4\u03ae\u03bc\u03b9\u03bf \u0395\u03c0\u03b9\u03c3\u03c4\u03ae\u03bc\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03a4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2, \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03b1\u03c0\u03cc \u03ac\u03bb\u03bb\u03b1 \u03c0\u03b1\u03bd\u03b5\u03c0\u03b9\u03c3\u03c4\u03ae\u03bc\u03b9\u03b1 \u03b4\u03b9\u03b1\u03c0\u03af\u03c3\u03c4\u03c9\u03c3\u03b1\u03bd, \u03cc\u03c4\u03b9 \u03bf\u03b9 \u03ac\u03bd\u03b4\u03c1\u03b5\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03c7\u03c9\u03c1\u03b9\u03ba\u03ae \u03ba\u03b1\u03c4\u03b1\u03c4\u03cc\u03c0\u03b9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b9\u03bf \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03bf\u03af \u03c3\u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03bd\u03cc\u03b7\u03c3\u03b7 \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ce\u03bd \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03c4\u03b1\u03c7\u03cd\u03c4\u03b5\u03c1\u03b7 \u03ac\u03c6\u03b9\u03be\u03b7 \u03c3\u03b5 \u03ba\u03ac\u03c0\u03bf\u03b9\u03bf\u03bd \u03c0\u03c1\u03bf\u03bf\u03c1\u03b9\u03c3\u03bc\u03cc. \u039f\u03b9 \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03ad\u03c2 \u03bb\u03ad\u03bd\u03b5 \u03cc\u03c4\u03b9 \u03b1\u03c5\u03c4\u03cc \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bf\u03c6\u03b5\u03af\u03bb\u03b5\u03c4\u03b1\u03b9 -\u03b5\u03bd \u03bc\u03ad\u03c1\u03b5\u03b9- \u03c3\u03c4\u03b1 \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03c4\u03b5\u03c3\u03c4\u03bf\u03c3\u03c4\u03b5\u03c1\u03cc\u03bd\u03b7\u03c2 , \u03c0\u03bf\u03c5 \u03ad\u03c7\u03bf\u03c5\u03bd \u03bc\u03b5 \u03c6\u03c5\u03c3\u03b9\u03ba\u03cc \u03c4\u03c1\u03cc\u03c0\u03bf \u03bf\u03b9 \u03ac\u03bd\u03c4\u03c1\u03b5\u03c2 \u03c3\u03c4\u03bf\u03bd \u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc \u03c4\u03bf\u03c5\u03c2<span style=\"color: #00ccff\">.<sup id=\"cite_ref-14\" class=\"reference\"><a style=\"color: #00ccff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%A1%CF%8C%CE%BB%CE%BF%CF%82_%CF%86%CF%8D%CE%BB%CE%BF%CF%85#cite_note-14\">[14]<\/a><\/sup><sup id=\"cite_ref-15\" class=\"reference\"><a style=\"color: #00ccff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%A1%CF%8C%CE%BB%CE%BF%CF%82_%CF%86%CF%8D%CE%BB%CE%BF%CF%85#cite_note-15\">[15]<\/a><\/sup><\/span><\/p>\n<p>\u03a3\u03c5\u03b3\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03b1\u03c0\u03b5\u03b9\u03ba\u03cc\u03bd\u03b9\u03c3\u03b7 -\u03bc\u03b9\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b3\u03af\u03bd\u03b5\u03b9 \u03c0\u03bf\u03c4\u03ad \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd \u03b4\u03cd\u03bf \u03c6\u03cd\u03bb\u03c9\u03bd-<span style=\"color: #00ccff\">\u00a0<sup id=\"cite_ref-:0_16-0\" class=\"reference\"><a style=\"color: #00ccff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%A1%CF%8C%CE%BB%CE%BF%CF%82_%CF%86%CF%8D%CE%BB%CE%BF%CF%85#cite_note-:0-16\">[16]<\/a><\/sup><\/span>\u03ad\u03b4\u03b5\u03b9\u03be\u03b5 \u03cc\u03c4\u03b9 \u03c3\u03c4\u03bf\u03bd \u03b5\u03b3\u03ba\u03ad\u03c6\u03b1\u03bb\u03bf \u03c4\u03c9\u03bd \u03b1\u03bd\u03b4\u03c1\u03ce\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03bd\u03b5\u03c5\u03c1\u03b9\u03ba\u03ad\u03c2 \u03c3\u03c5\u03bd\u03ac\u03c8\u03b5\u03b9\u03c2 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03bf\u03c5 \u03c0\u03c1\u03cc\u03c3\u03b8\u03b9\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u03bf\u03c0\u03af\u03c3\u03b8\u03b9\u03bf\u03c5 \u03bb\u03bf\u03b2\u03bf\u03cd \u03c4\u03bf\u03c5 \u03b5\u03b3\u03ba\u03b5\u03c6\u03ac\u03bb\u03bf\u03c5. \u0391\u03c5\u03c4\u03cc \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03bf \u03b1\u03bd\u03b4\u03c1\u03b9\u03ba\u03cc\u03c2 \u03b5\u03b3\u03ba\u03ad\u03c6\u03b1\u03bb\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03bf\u03bc\u03b7\u03bc\u03ad\u03bd\u03bf\u03c2 \u03ad\u03c4\u03c3\u03b9 \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03b4\u03b9\u03b5\u03c5\u03ba\u03bf\u03bb\u03cd\u03bd\u03b5\u03b9 \u03c4\u03b7 \u03b4\u03b9\u03b1\u03c3\u03cd\u03bd\u03b4\u03b5\u03c3\u03b7 \u03b1\u03bd\u03ac\u03bc\u03b5\u03c3\u03b1 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03c4\u03af\u03bb\u03b7\u03c8\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03c3\u03c5\u03bd\u03c4\u03bf\u03bd\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7 \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03c9\u03bd \u03ba\u03b9\u03bd\u03ae\u03c3\u03b5\u03c9\u03bd.<\/p>\n<p>\u0391\u03c0\u03cc \u03c4\u03b7\u03bd \u03ac\u03bb\u03bb\u03b7, \u03bf \u03b5\u03b3\u03ba\u03ad\u03c6\u03b1\u03bb\u03bf\u03c2 \u03c4\u03c9\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd \u03ad\u03c7\u03b5\u03b9 \u03c3\u03b1\u03c6\u03ce\u03c2 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u00ab\u03ba\u03b1\u03bb\u03c9\u03b4\u03af\u03c9\u03c3\u03b7\u00bb \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03bf\u03c5 \u03b1\u03c1\u03b9\u03c3\u03c4\u03b5\u03c1\u03bf\u03cd \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u03b4\u03b5\u03be\u03b9\u03bf\u03cd \u03b7\u03bc\u03b9\u03c3\u03c6\u03b1\u03b9\u03c1\u03af\u03bf\u03c5, \u03c0\u03c1\u03ac\u03b3\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03b4\u03b9\u03b5\u03c5\u03ba\u03bf\u03bb\u03cd\u03bd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03ba\u03bf\u03b9\u03bd\u03c9\u03bd\u03af\u03b1 \u03b1\u03bd\u03ac\u03bc\u03b5\u03c3\u03b1 \u03c3\u03c4\u03b7 \u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b1\u03af\u03c3\u03b8\u03b7\u03c3\u03b7.<\/p>\n<p>\u03c3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03bf\u03c5\u03c2 \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03ad\u03c2, \u03ba\u03b1\u03c4\u03ac \u03bc\u03ad\u03c3\u03bf \u03cc\u03c1\u03bf \u03bf\u03b9 \u03ac\u03bd\u03b4\u03c1\u03b5\u03c2 \u03bc\u03b1\u03b8\u03b1\u03af\u03bd\u03bf\u03c5\u03bd \u03ba\u03b1\u03b9 \u03b5\u03ba\u03c4\u03b5\u03bb\u03bf\u03cd\u03bd \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b1 \u03bc\u03b9\u03b1 \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03b7 \u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1, \u03cc\u03c0\u03c9\u03c2 \u03bd\u03b1 \u03ba\u03ac\u03bd\u03bf\u03c5\u03bd \u03c0\u03bf\u03b4\u03ae\u03bb\u03b1\u03c4\u03bf \u03ae \u03bd\u03b1 \u03c0\u03c1\u03bf\u03c3\u03b1\u03bd\u03b1\u03c4\u03bf\u03bb\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf\u03bd \u03c7\u03ce\u03c1\u03bf (\u03c0.\u03c7. \u03b4\u03b9\u03b1\u03b2\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c7\u03ac\u03c1\u03c4\u03b5\u03c2). \u0391\u03c0\u03cc \u03c4\u03b7\u03bd \u03ac\u03bb\u03bb\u03b7, \u03bf\u03b9 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae, \u03b1\u03bd\u03ce\u03c4\u03b5\u03c1\u03b7 \u03bc\u03bd\u03ae\u03bc\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bd\u03b1\u03b9\u03c3\u03b8\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03bd\u03bf\u03b7\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b5\u03c2 \u03ba\u03bf\u03b9\u03bd\u03c9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b5\u03be\u03b9\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2, \u03bc\u03b5 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b1 \u03b5\u03c6\u03bf\u03b4\u03b9\u03b1\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03b1\u03c0\u03b1\u03b9\u03c4\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b3\u03af\u03bd\u03bf\u03c5\u03bd \u03c0\u03bf\u03bb\u03bb\u03ac \u03c0\u03c1\u03ac\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c4\u03b1\u03c5\u03c4\u03cc\u03c7\u03c1\u03bf\u03bd\u03b1 \u03ae \u03bd\u03b1 \u03b2\u03c1\u03b5\u03b8\u03bf\u03cd\u03bd \u03bb\u03cd\u03c3\u03b5\u03b9\u03c2 \u03bc\u03ad\u03c3\u03b1 \u03b1\u03c0\u03cc \u03bf\u03bc\u03b1\u03b4\u03b9\u03ba\u03ae \u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1.<\/p>\n<p>\u038c\u03c3\u03bf\u03bd \u03b1\u03c6\u03bf\u03c1\u03ac \u03c4\u03b7\u03bd \u00ab\u03ba\u03b1\u03bb\u03c9\u03b4\u03af\u03c9\u03c3\u03b7\u00bb \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd \u03b4\u03cd\u03bf \u03b7\u03bc\u03b9\u03c3\u03c6\u03b1\u03b9\u03c1\u03af\u03c9\u03bd, \u03ba\u03b1\u03c4&#8217; \u03b5\u03be\u03b1\u03af\u03c1\u03b5\u03c3\u03b7 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03ac\u03bd\u03b4\u03c1\u03b5\u03c2 \u03b1\u03c5\u03c4\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03bc\u03cc\u03bd\u03bf \u03c3\u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b5\u03b3\u03ba\u03b5\u03c6\u03b1\u03bb\u03af\u03b4\u03b1, \u03c0\u03bf\u03c5 \u03b1\u03c6\u03bf\u03c1\u03ac \u03c4\u03bf\u03bd \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03c4\u03c9\u03bd \u03ba\u03b9\u03bd\u03ae\u03c3\u03b5\u03c9\u03bd, \u03b5\u03bd\u03ce \u03b1\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03b1 \u03c3\u03b5 \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ae \u03bf\u03b9 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03c3\u03c5\u03bd\u03b4\u03ad\u03c3\u03b5\u03b9\u03c2 \u03bc\u03ad\u03c3\u03b1 \u03c3\u03b5 \u03ba\u03ac\u03b8\u03b5 \u03b7\u03bc\u03b9\u03c3\u03c6\u03b1\u03af\u03c1\u03b9\u03bf \u03be\u03b5\u03c7\u03c9\u03c1\u03b9\u03c3\u03c4\u03ac. \u0391\u03c5\u03c4\u03cc \u03b4\u03af\u03bd\u03b5\u03b9 \u03ad\u03bd\u03b1 \u03c0\u03bb\u03b5\u03bf\u03bd\u03ad\u03ba\u03c4\u03b7\u03bc\u03b1 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03ac\u03bd\u03b4\u03c1\u03b5\u03c2 \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03bf\u03bd \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03c4\u03c9\u03bd \u03bc\u03c5\u03ce\u03bd \u03c4\u03bf\u03c5\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03c3\u03c5\u03bd\u03c4\u03bf\u03bd\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7 \u03b1\u03b9\u03c3\u03b8\u03b7\u03c4\u03b9\u03ba\u03bf\u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03c4\u03af\u03bb\u03b7\u03c8\u03b7, \u03ba\u03ac\u03c4\u03b9 \u03c0\u03bf\u03c5 \u03c4\u03bf\u03c5\u03c2 \u03b5\u03c0\u03b9\u03c4\u03c1\u03ad\u03c0\u03b5\u03b9 \u03b3\u03b9\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b4\u03b5\u03b9\u03b3\u03bc\u03b1 \u03bd\u03b1 \u03bc\u03ac\u03b8\u03bf\u03c5\u03bd \u03b5\u03c5\u03ba\u03bf\u03bb\u03cc\u03c4\u03b5\u03c1\u03b1 \u03bd\u03b1 \u03ba\u03ac\u03bd\u03bf\u03c5\u03bd \u03ba\u03b1\u03bb\u03cc \u03c3\u03ba\u03b9.<\/p>\n<p>\u038c\u03c3\u03bf \u03bc\u03b5\u03b3\u03b1\u03bb\u03ce\u03bd\u03bf\u03c5\u03bd \u03c4\u03b1 \u03b1\u03b3\u03cc\u03c1\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b1 \u03ba\u03bf\u03c1\u03af\u03c4\u03c3\u03b9\u03b1, \u03c4\u03cc\u03c3\u03bf \u03bf\u03b9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ad\u03c2 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03b5\u03b3\u03ba\u03b5\u03c6\u03ac\u03bb\u03bf\u03c5\u03c2 \u03c4\u03bf\u03c5\u03c2 \u03b3\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b9\u03bf \u03b1\u03b9\u03c3\u03b8\u03b7\u03c4\u03ad\u03c2, \u03b5\u03bd\u03ce \u03c0\u03c1\u03b9\u03bd \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03c4\u03c9\u03bd 13 \u03b5\u03c4\u03ce\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03bf\u03bb\u03cd \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2, \u03b4\u03b7\u03bb\u03b1\u03b4\u03ae \u03bf\u03b9 \u03b5\u03b3\u03ba\u03ad\u03c6\u03b1\u03bb\u03bf\u03b9 \u03c4\u03c9\u03bd \u03b4\u03cd\u03bf \u03c6\u03cd\u03bb\u03c9\u03bd \u03c3\u03c4\u03b7\u03bd \u03c0\u03b1\u03b9\u03b4\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03bc\u03bf\u03b9\u03ac\u03b6\u03bf\u03c5\u03bd \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03bf\u03c5\u03c2.<sup id=\"cite_ref-:0_16-1\" class=\"reference\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%A1%CF%8C%CE%BB%CE%BF%CF%82_%CF%86%CF%8D%CE%BB%CE%BF%CF%85#cite_note-:0-16\">[16]<\/a><\/sup><\/p>\n<figure id=\"attachment_639\" aria-describedby=\"caption-attachment-639\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-639\" src=\"http:\/\/mde.biologia.gr\/koupa\/wp-content\/uploads\/sites\/23\/2018\/05\/brainpnas-300x300.jpg\" alt=\"\" width=\"300\" height=\"300\" srcset=\"https:\/\/mde.biologia.gr\/koupa\/wp-content\/uploads\/sites\/23\/2018\/05\/brainpnas-300x300.jpg 300w, https:\/\/mde.biologia.gr\/koupa\/wp-content\/uploads\/sites\/23\/2018\/05\/brainpnas-150x150.jpg 150w, https:\/\/mde.biologia.gr\/koupa\/wp-content\/uploads\/sites\/23\/2018\/05\/brainpnas-400x400.jpg 400w, https:\/\/mde.biologia.gr\/koupa\/wp-content\/uploads\/sites\/23\/2018\/05\/brainpnas-120x120.jpg 120w, https:\/\/mde.biologia.gr\/koupa\/wp-content\/uploads\/sites\/23\/2018\/05\/brainpnas-80x80.jpg 80w, https:\/\/mde.biologia.gr\/koupa\/wp-content\/uploads\/sites\/23\/2018\/05\/brainpnas.jpg 549w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-639\" class=\"wp-caption-text\">\u03bf\u03b9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ad\u03c2 \u03c3\u03c4\u03b7\u03bd \u03ba\u03b1\u03bb\u03c9\u03b4\u03af\u03c9\u03c3\u03b7 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03b1\u03bd\u03b4\u03c1\u03ce\u03bd (\u03bc\u03c0\u03bb\u03b5 \u03c7\u03c1\u03ce\u03bc\u03b1) \u03ba\u03b1\u03b9 \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd (\u03c0\u03bf\u03c1\u03c4\u03bf\u03ba\u03b1\u03bb\u03af)<\/figcaption><\/figure>\n<\/div>\n<\/div>\n<p><strong><span style=\"color: #ff0000\">\u03a4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03bf \u03c0\u03b1\u03c1\u03b1\u03b8\u03ad\u03c4\u03c9 \u03c4\u03bf \u03bb\u03ae\u03bc\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03b4\u03b7\u03bc\u03b9\u03bf\u03cd\u03c1\u03b3\u03b7\u03c3\u03b1:<\/span><\/strong><\/p>\n<p>&nbsp;<\/p>\n<h1 id=\"firstHeading\" class=\"firstHeading\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82\">\u039a\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2<\/a><\/h1>\n<div id=\"bodyContent\" class=\"mw-body-content\">\n<div id=\"siteSub\" class=\"noprint\">\u0391\u03c0\u03cc \u03c4\u03b7 \u0392\u03b9\u03ba\u03b9\u03c0\u03b1\u03af\u03b4\u03b5\u03b9\u03b1, \u03c4\u03b7\u03bd \u03b5\u03bb\u03b5\u03cd\u03b8\u03b5\u03c1\u03b7 \u03b5\u03b3\u03ba\u03c5\u03ba\u03bb\u03bf\u03c0\u03b1\u03af\u03b4\u03b5\u03b9\u03b1<\/div>\n<div id=\"contentSub\"><\/div>\n<div id=\"jump-to-nav\" class=\"mw-jump\"><\/div>\n<div id=\"mw-content-text\" class=\"mw-content-ltr\" dir=\"ltr\" lang=\"el\">\n<div class=\"mw-parser-output\">\n<p><b>\u039a\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2<\/b>\u00a0(Cysteine Aspartate Specific Proteases). \u039f\u03b9 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03c1\u03c9\u03c4\u03b5\u03ac\u03c3\u03b5\u03c2 \u03bc\u03b5 \u03c0\u03bf\u03bb\u03cd \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03b4\u03c1\u03ac\u03c3\u03b7. \u0394\u03b9\u03b1\u03b4\u03c1\u03b1\u03bc\u03b1\u03c4\u03af\u03b6\u03bf\u03c5\u03bd \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc \u03c1\u03cc\u03bb\u03bf \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1 \u03c4\u03b7\u03c2<span style=\"color: #00ccff\">\u00a0<a style=\"color: #00ccff\" title=\"\u0391\u03c0\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%91%CF%80%CF%8C%CF%80%CF%84%CF%89%CF%83%CE%B7\"><u><b>\u03b1\u03c0\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7\u03c2<\/b><\/u><\/a><\/span>, \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1\u03c2 \u03c4\u03cd\u03c0\u03bf\u03c2 \u03c0\u03c1\u03bf\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1\u03c4\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5<span style=\"color: #00ccff\">\u00a0<a style=\"color: #00ccff\" title=\"\u039a\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03cc\u03c2 \u03b8\u03ac\u03bd\u03b1\u03c4\u03bf\u03c2\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CF%85%CF%84%CF%84%CE%B1%CF%81%CE%B9%CE%BA%CF%8C%CF%82_%CE%B8%CE%AC%CE%BD%CE%B1%CF%84%CE%BF%CF%82\"><u><b>\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03bf\u03cd \u03b8\u03b1\u03bd\u03ac\u03c4\u03bf\u03c5<\/b><\/u><\/a><\/span>, \u03bf \u03bf\u03c0\u03bf\u03af\u03bf\u03c2 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03b5\u03bd\u03cc\u03c2 \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03bf\u03c5 \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03bf\u03cd \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03cd. \u039f\u03b9 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2, \u03ba\u03cc\u03b2\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03c0\u03bf\u03bb\u03c5\u03c0\u03b5\u03c0\u03c4\u03b9\u03b4\u03b9\u03ba\u03ae \u03b1\u03bb\u03c5\u03c3\u03af\u03b4\u03b1 \u03bc\u03cc\u03bd\u03bf \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03c5\u03c0\u03cc\u03bb\u03b5\u03b9\u03bc\u03bc\u03b1 \u03b1\u03c3\u03c0\u03b1\u03c1\u03c4\u03b9\u03ba\u03bf\u03cd \u03bf\u03be\u03ad\u03bf\u03c2. \u03a5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03c3\u03c4\u03bf \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03cc\u03c0\u03bb\u03b1\u03c3\u03bc\u03b1 \u03c5\u03c0\u03cc \u03bc\u03bf\u03c1\u03c6\u03ae \u03c0\u03c1\u03bf\u03b5\u03bd\u03b6\u03cd\u03bc\u03c9\u03bd.<span style=\"color: #00ccff\"><sup id=\"cite_ref-1\" class=\"reference\"><a style=\"color: #00ccff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_note-1\">[1]<\/a><\/sup><\/span>\u00a0\u039f\u03b9 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2, \u03c3\u03c4\u03bf \u03b5\u03bd\u03b5\u03c1\u03b3\u03cc \u03c4\u03bf\u03c5\u03c2 \u03ba\u03ad\u03bd\u03c4\u03c1\u03bf, \u03c6\u03ad\u03c1\u03bf\u03c5\u03bd \u03c4\u03bf\u00a0<span style=\"color: #00ccff\"><a style=\"color: #00ccff\" title=\"\u0391\u03bc\u03b9\u03bd\u03bf\u03be\u03ad\u03b1\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%91%CE%BC%CE%B9%CE%BD%CE%BF%CE%BE%CE%AD%CE%B1\"><u>\u03b1\u03bc\u03b9\u03bd\u03bf\u03be\u03cd<\/u><\/a>\u00a0<u><b><a style=\"color: #00ccff\" title=\"\u039a\u03c5\u03c3\u03c4\u03b5\u0390\u03bd\u03b7\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CF%85%CF%83%CF%84%CE%B5%CE%90%CE%BD%CE%B7\">\u03ba\u03c5\u03c3\u03c4\u03b5\u0390\u03bd\u03b7<\/a><\/b><\/u>\u00a0.<\/span> \u0397 \u03c0\u03c1\u03ce\u03c4\u03b7 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b7 \u03c0\u03bf\u03c5 \u03b1\u03bd\u03b1\u03b3\u03bd\u03c9\u03c1\u03af\u03c3\u03b8\u03b7\u03ba\u03b5 \u03ae\u03c4\u03b1\u03bd \u03c4\u03bf \u03bc\u03b5\u03c4\u03b1\u03c4\u03c1\u03b5\u03c0\u03c4\u03b9\u03ba\u03cc\u00a0<a title=\"\u0388\u03bd\u03b6\u03c5\u03bc\u03bf\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%88%CE%BD%CE%B6%CF%85%CE%BC%CE%BF\"><u>\u03ad\u03bd\u03b6\u03c5\u03bc\u03bf<\/u><\/a>\u00a0\u03c4\u03b7\u03c2 \u03b9\u03bd\u03c4\u03b5\u03c1\u03bb\u03b5\u03c5\u03ba\u03af\u03bd\u03b7\u03c2-1\u03b2 (ICE, caspase-1) \u03ba\u03b1\u03b9 \u03b1\u03c1\u03c7\u03b9\u03ba\u03ac \u03c4\u03b1\u03c5\u03c4\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b5, \u03c9\u03c2 \u03b7 \u03c5\u03c0\u03b5\u03cd\u03b8\u03c5\u03bd\u03b7\u00a0<a title=\"\u03a0\u03c1\u03c9\u03c4\u03b5\u03ac\u03c3\u03b7\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%A0%CF%81%CF%89%CF%84%CE%B5%CE%AC%CF%83%CE%B7\">\u03c0\u03c1\u03c9\u03c4\u03b5\u03ac\u03c3\u03b7<\/a>\u00a0\u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03c9\u03c1\u03af\u03bc\u03b1\u03bd\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03bf-\u03b9\u03bd\u03c4\u03b5\u03c1\u03bb\u03b5\u03c5\u03ba\u03af\u03bd\u03b7\u03c2 (IL)-1\u03b2 \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03bf-\u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b7, \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03b5\u03bd\u03b5\u03c1\u03b3\u03ae \u03bc\u03bf\u03c1\u03c6\u03ae \u03c4\u03b7\u03c2.<span style=\"color: #00ccff\"><sup id=\"cite_ref-2\" class=\"reference\"><a style=\"color: #00ccff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_note-2\">[2]<\/a><\/sup><\/span><\/p>\n<h3><span id=\".CE.94.CE.BF.CE.BC.CE.B9.CE.BA.CE.AC_.CF.87.CE.B1.CF.81.CE.B1.CE.BA.CF.84.CE.B7.CF.81.CE.B9.CF.83.CF.84.CE.B9.CE.BA.CE.AC_.CF.84.CF.89.CE.BD_.CE.BC.CE.B5.CE.BB.CF.8E.CE.BD_.CF.84.CE.B7.CF.82_.CE.BF.CE.B9.CE.BA.CE.BF.CE.B3.CE.AD.CE.BD.CE.B5.CE.B9.CE.B1.CF.82_.CF.84.CF.89.CE.BD_.CE.BA.CE.B1.CF.83.CF.80.CE.B1.CF.83.CF.8E.CE.BD\"><\/span><span id=\"\u0394\u03bf\u03bc\u03b9\u03ba\u03ac_\u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac_\u03c4\u03c9\u03bd_\u03bc\u03b5\u03bb\u03ce\u03bd_\u03c4\u03b7\u03c2_\u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2_\u03c4\u03c9\u03bd_\u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd\" class=\"mw-headline\">\u0394\u03bf\u03bc\u03b9\u03ba\u03ac \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c4\u03c9\u03bd \u03bc\u03b5\u03bb\u03ce\u03bd \u03c4\u03b7\u03c2 \u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 \u03c4\u03c9\u03bd \u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd<\/span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[<\/span><span style=\"color: #00ccff\"><a class=\"mw-editsection-visualeditor\" style=\"color: #00ccff\" title=\"\u0395\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03b5\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2: \u0394\u03bf\u03bc\u03b9\u03ba\u03ac \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c4\u03c9\u03bd \u03bc\u03b5\u03bb\u03ce\u03bd \u03c4\u03b7\u03c2 \u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 \u03c4\u03c9\u03bd \u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd\" href=\"https:\/\/el.wikipedia.org\/w\/index.php?title=%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82&amp;veaction=edit&amp;section=1\">\u0395\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1<\/a><span class=\"mw-editsection-divider\">\u00a0|\u00a0<\/span><a style=\"color: #00ccff\" title=\"\u0395\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03b5\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2: \u0394\u03bf\u03bc\u03b9\u03ba\u03ac \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c4\u03c9\u03bd \u03bc\u03b5\u03bb\u03ce\u03bd \u03c4\u03b7\u03c2 \u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 \u03c4\u03c9\u03bd \u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd\" href=\"https:\/\/el.wikipedia.org\/w\/index.php?title=%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82&amp;action=edit&amp;section=1\">\u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03ba\u03ce\u03b4\u03b9\u03ba\u03b1<\/a><span class=\"mw-editsection-bracket\">]<\/span><\/span><\/span><\/h3>\n<p>\u039f\u03b9 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ad\u03c7\u03bf\u03c5\u03bd \u03c3\u03c4\u03b7\u03bd \u03b1\u03c0\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7 \u03b4\u03b9\u03b1\u03ba\u03c1\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b4\u03cd\u03bf \u03ba\u03b1\u03c4\u03b7\u03b3\u03bf\u03c1\u03af\u03b5\u03c2:<\/p>\n<p><b>\u03c4\u03b9\u03c2 \u03b5\u03bd\u03b1\u03c1\u03ba\u03c4\u03ae\u03c1\u03b9\u03b5\u03c2 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2<\/b>\u00a0(initiator), \u03c3\u03c4\u03b9\u03c2 \u03bf\u03c0\u03bf\u03af\u03b5\u03c2 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bf\u03b9 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2-2, -8, -9, \u03ba\u03b1\u03b9 \u201310, \u03ba\u03b1\u03b9<\/p>\n<p><b>\u03c4\u03b9\u03c2 \u03c4\u03b5\u03bb\u03b5\u03c3\u03c4\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2<\/b>\u00a0(effector), \u03c3\u03c4\u03b9\u03c2 \u03bf\u03c0\u03bf\u03af\u03b5\u03c2 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bf\u03b9 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2-3, -6, \u03ba\u03b1\u03b9 -7 (\u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 1).<\/p>\n<div class=\"thumb tright\">\n<div class=\"thumbinner\">\n<p><a class=\"image\" href=\"https:\/\/commons.wikimedia.org\/wiki\/File:Kaspases.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"thumbimage\" src=\"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/9\/9f\/Kaspases.jpg\/220px-Kaspases.jpg\" alt=\"\" width=\"220\" height=\"155\" \/><\/a><\/p>\n<div class=\"thumbcaption\">\n<div class=\"magnify\"><\/div>\n<p><em><strong>\u0395\u03b9\u03ba. 1<\/strong><b>. \u0397 \u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1 \u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd<\/b>.\u00a0<b>\u0391<\/b>: \u039f\u03b9 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2 \u03b4\u03b9\u03b1\u03c7\u03c9\u03c1\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b4\u03cd\u03bf \u03ba\u03cd\u03c1\u03b9\u03b5\u03c2 \u03c5\u03c0\u03bf\u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b5\u03c2 (ICE, CED-3). \u039c\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03b9\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u03bf\u03bb\u03c5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b9\u03b4\u03b9\u03b1\u03b9\u03c4\u03b5\u03c1\u03cc\u03c4\u03b7\u03c4\u03ad\u03c2 \u03c4\u03bf\u03c5\u03c2, \u03bf\u03b9 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2 \u03b4\u03b9\u03b1\u03b9\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03c3\u03b5 \u03c4\u03c1\u03b5\u03b9\u03c2 \u03bf\u03bc\u03ac\u03b4\u03b5\u03c2: \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03b9\u03c2 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2 (\u03bc\u03c0\u03bb\u03b5) \u03c0\u03bf\u03c5 \u03bc\u03b5\u03c3\u03bf\u03bb\u03b1\u03b2\u03bf\u03cd\u03bd \u03c3\u03c4\u03b7\u03bd \u03c9\u03c1\u03af\u03bc\u03b1\u03bd\u03c3\u03b7 \u03c4\u03c9\u03bd \u03ba\u03c5\u03c4\u03bf\u03ba\u03b9\u03bd\u03ce\u03bd, \u03b5\u03bd\u03ce \u03bf\u03b9 \u03b1\u03c0\u03bf\u03c0\u03c4\u03c9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03af\u03c4\u03b5 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03ad\u03c2 \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03bf\u03cd \u03b8\u03b1\u03bd\u03ac\u03c4\u03bf\u03c5 (\u03ba\u03cc\u03ba\u03ba\u03b9\u03bd\u03bf) \u03b5\u03af\u03c4\u03b5 \u03b1\u03bd\u03bf\u03b4\u03b9\u03ba\u03bf\u03af \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03ad\u03c2 (\u03c0\u03c1\u03ac\u03c3\u03b9\u03bd\u03bf).\u00a0<b>\u0392<\/b>: \u039a\u03c1\u03c5\u03c3\u03c4\u03b1\u03bb\u03bb\u03b9\u03ba\u03ae \u03b4\u03bf\u03bc\u03ae \u03ce\u03c1\u03b9\u03bc\u03b7\u03c2 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b7\u03c2-3 \u03c3\u03b5 \u03c3\u03cd\u03bc\u03c0\u03bb\u03b5\u03b3\u03bc\u03b1 \u03bc\u03b5 \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03b1 \u03c4\u03b5\u03c4\u03c1\u03b1\u03c0\u03b5\u03c0\u03c4\u03b9\u03b4\u03b9\u03ba\u03ae\u03c2 \u03b1\u03bb\u03b4\u03b5\u03b0\u03b4\u03b7\u03c2 (\u03ba\u03af\u03c4\u03c1\u03b9\u03bd\u03bf). \u0397 \u03b5\u03bd\u03b5\u03c1\u03b3\u03ae 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class=\"reference\"><a style=\"color: #00ccff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_note-:0-3\">[3]<\/a><\/sup><\/span><\/li>\n<\/ul>\n<p>\u039f\u03b9 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2 \u03bc\u03b5\u03c4\u03b5\u03c4\u03c1\u03ad\u03c0\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c0\u03bb\u03ae\u03c1\u03c9\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ad\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u03ac\u03c3\u03b5\u03c2, \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03b4\u03cd\u03bf \u03b3\u03b5\u03b3\u03bf\u03bd\u03cc\u03c4\u03b1 \u03ba\u03b1\u03c4\u03ac\u03c4\u03bc\u03b7\u03c3\u03b7\u03c2, \u03c4\u03b1 \u03bf\u03c0\u03bf\u03af\u03b1 \u03c3\u03c5\u03bc\u03b2\u03b1\u03af\u03bd\u03bf\u03c5\u03bd \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03ba\u03b1\u03c4\u03ac\u03bb\u03bf\u03b9\u03c0\u03b1 \u03b1\u03c3\u03c0\u03b1\u03c1\u03c4\u03b9\u03ba\u03bf\u03cd \u03bf\u03be\u03ad\u03bf\u03c2 (Asp)<sup id=\"cite_ref-4\" class=\"reference\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_note-4\"><span style=\"color: #00ccff\">[4]<\/span><\/a><\/sup>\u00a0\u0397 \u03bc\u03b5\u03c4\u03b1\u03c4\u03c1\u03bf\u03c0\u03ae \u03b1\u03c5\u03c4\u03ae, \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03c7\u03ce\u03c1\u03b1 \u03bc\u03ad\u03c3\u03c9 \u03ba\u03b1\u03c4\u03ac\u03c4\u03bc\u03b7\u03c3\u03b7\u03c2, \u03b5\u03af\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03b5\u03b1\u03c5\u03c4\u03cc \u03c4\u03bf\u03c5\u03c2 \u03b5\u03af\u03c4\u03b5 \u03b1\u03c0\u03cc \u03ac\u03bb\u03bb\u03b5\u03c2 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2: \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03ba\u03b1\u03c4\u03ac\u03c4\u03bc\u03b7\u03c3\u03b7 \u03b4\u03b9\u03b1\u03c7\u03c9\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03c0\u03c1\u03cc\u03b4\u03c1\u03bf\u03bc\u03b7 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ae (prodomain) \u03b1\u03c0\u03cc 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\u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd, \u03c0\u03c1\u03bf\u03ba\u03b5\u03b9\u03bc\u03ad\u03bd\u03bf\u03c5 \u03bf\u03b9 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2 \u03bd\u03b1 \u03b1\u03c0\u03bf\u03ba\u03c4\u03ae\u03c3\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b9\u03ba\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bd\u03b1 \u03b1\u03c5\u03c4\u03bf\u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03ae \u03bd\u03b1 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ac\u03bb\u03bb\u03b5\u03c2 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2, \u03c9\u03c2 \u03c4\u03bc\u03ae\u03bc\u03b1 \u03b5\u03bd\u03cc\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c1\u03c1\u03ac\u03ba\u03c4\u03b7 \u03b5\u03bd\u03af\u03c3\u03c7\u03c5\u03c3\u03b7\u03c2<span style=\"color: #00ccff\">.<sup id=\"cite_ref-:0_3-1\" class=\"reference\"><a style=\"color: #00ccff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_note-:0-3\">[3]<\/a><\/sup><\/span>\u00a0\u039f\u03b9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2 \u03b4\u03b9\u03b1\u03b8\u03ad\u03c4\u03bf\u03c5\u03bd \u03b4\u03cd\u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b4\u03bf\u03bc\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ad\u03c2:<\/p>\n<ol>\n<li>\u0394\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03c5\u03bd \u03c3\u03c4\u03b1 \u03bc\u03ae\u03ba\u03b7 \u03c4\u03c9\u03bd \u03c0\u03c1\u03cc\u03b4\u03c1\u03bf\u03bc\u03c9\u03bd \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ce\u03bd (prodomains), \u03cc\u03c0\u03c9\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bc\u03b9\u03bd\u03bf\u03be\u03b9\u03ba\u03ae \u03c4\u03bf\u03c5\u03c2 \u03b1\u03bb\u03bb\u03b7\u03bb\u03bf\u03c5\u03c7\u03af\u03b1. \u039c\u03b5\u03b3\u03ac\u03bb\u03b1 \u03c0\u03c1\u03cc\u03b4\u03c1\u03bf\u03bc\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ad\u03c2 \u03c4\u03c9\u03bd \u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd, \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03bf\u03cd\u03bd \u03c9\u03c2 \u03b4\u03b9\u03b1\u03bc\u03b5\u03c3\u03bf\u03bb\u03b1\u03b2\u03b7\u03c4\u03ad\u03c2 \u03c3\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd, \u03b3\u03b9\u03b1 \u03c0\u03c1\u03bf-\u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b7 \u03ae \u03b1\u03c0\u03bf\u03c0\u03c4\u03c9\u03c4\u03b9\u03ba\u03ac \u03c3\u03ae\u03bc\u03b1\u03c4\u03b1, \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b1\u03b8\u03ad\u03c4\u03bf\u03c5\u03bd \u03b1\u03bb\u03bb\u03b7\u03bb\u03bf\u03c5\u03c7\u03b9\u03ba\u03ac \u03bc\u03bf\u03c4\u03af\u03b2\u03b1 \u03c0\u03bf\u03c5 \u03c0\u03c1\u03bf\u03ac\u03b3\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b1\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03bc\u03b5 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03ac \u03bc\u03cc\u03c1\u03b9\u03b1 [caspase-recruitment domain (CARD) or death effector domain (DED)]<sup id=\"cite_ref-5\" class=\"reference\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_note-5\"><span style=\"color: #00ccff\">[5]<\/span><\/a><\/sup>\u00a0\u039f\u03b9 \u03b5\u03bd\u03b1\u03c1\u03ba\u03c4\u03ae\u03c1\u03b9\u03b5\u03c2 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2 (\u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b7-2, -8, -9, \u03ba\u03b1\u03b9 \u201310) \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03bc\u03b9\u03b1 \u03b5\u03ba\u03c4\u03b5\u03c4\u03b1\u03bc\u03ad\u03bd\u03b7 \u03b1\u03bc\u03b9\u03bd\u03bf\u03c4\u03b5\u03bb\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf-\u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ae (prodomain) (&gt;90 \u03b1\u03bc\u03b9\u03bd\u03bf\u03be\u03ad\u03b1) \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c4\u03bf\u03c5\u03c2, \u03b5\u03bd\u03ce \u03bf\u03b9 \u03c4\u03b5\u03bb\u03b5\u03c3\u03c4\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03ad\u03c7\u03bf\u03c5\u03bd \u03bc\u03b9\u03ba\u03c1\u03ad\u03c2 \u03c0\u03c1\u03cc\u03b4\u03c1\u03bf\u03bc\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ad\u03c2 (prodomains) \u03c4\u03c9\u03bd 20-30 \u03b1\u03bc\u03b9\u03bd\u03bf\u03be\u03ad\u03c9\u03bd<span style=\"color: #00ccff\"><sup id=\"cite_ref-6\" class=\"reference\"><a style=\"color: #00ccff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_note-6\">[6]<\/a><\/sup><\/span><\/li>\n<li>\u03a3\u03c4\u03b9\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u03ac\u03c3\u03b5\u03c2 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b4\u03b9\u03ac\u03ba\u03c1\u03b9\u03c3\u03b7, \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03b7\u03bd \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03b9\u03ac\u03b6\u03bf\u03c5\u03bd \u03b3\u03b9\u03b1 \u03c4\u03b1 \u03c5\u03c0\u03bf\u03c3\u03c4\u03c1\u03ce\u03bc\u03b1\u03c4\u03ac \u03c4\u03bf\u03c5\u03c2<span style=\"color: #00ccff\"><sup id=\"cite_ref-7\" class=\"reference\"><a style=\"color: #00ccff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_note-7\">[7]<\/a><\/sup><\/span>. \u0394\u03b9\u03b1\u03b8\u03ad\u03c4\u03bf\u03c5\u03bd S2, S3, \u03ba\u03b1\u03b9 S4 \u03b8\u03ad\u03c3\u03b5\u03b9\u03c2 \u03c3\u03cd\u03bd\u03b4\u03b5\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b7\u03c2 \u03bc\u03b5 \u03c4\u03bf \u03c5\u03c0\u03cc\u03c3\u03c4\u03c1\u03c9\u03bc\u03b1, \u03bf\u03b9 \u03bf\u03c0\u03bf\u03af\u03b5\u03c2 \u03cc\u03bc\u03c9\u03c2 \u03c0\u03bf\u03b9\u03ba\u03af\u03bb\u03bf\u03c5\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac, \u03ad\u03c7\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c9\u03c2 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c4\u03b7\u03bd \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7 \u03bc\u03af\u03b1\u03c2 \u03c0\u03bf\u03b9\u03ba\u03b9\u03bb\u03af\u03b1\u03c2 \u03bc\u03bf\u03c1\u03c6\u03ce\u03bd \u03c3\u03c5\u03b3\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 \u03bc\u03b5 \u03c4\u03bf \u03c5\u03c0\u03cc\u03c3\u03c4\u03c1\u03c9\u03bc\u03b1 \u03c3\u03c4\u03b9\u03c2 \u03b8\u03ad\u03c3\u03b5\u03b9\u03c2 P2, P3, P4, \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03b1, \u03b1\u03bd\u03b5\u03be\u03ac\u03c1\u03c4\u03b7\u03c4\u03b1 \u03b1\u03c0\u03cc \u03c4\u03bf \u03b3\u03b5\u03b3\u03bf\u03bd\u03cc\u03c2, \u03cc\u03c4\u03b9 \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03bf\u03c0\u03c9\u03c3\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03b1\u03c3\u03c0\u03b1\u03c1\u03c4\u03b9\u03ba\u03cc \u03bf\u03be\u03cd \u03c3\u03c4\u03b7\u03bd P1 <span style=\"color: #00ccff\"><span style=\"color: #000000\">\u03b8\u03ad\u03c3\u03b7<\/span><sup id=\"cite_ref-8\" class=\"reference\"><a style=\"color: #00ccff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_note-8\">[8]<\/a><\/sup><sup id=\"cite_ref-9\" class=\"reference\"><a style=\"color: #00ccff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_note-9\">[9]<\/a><\/sup><\/span>\u00a0\u0397 \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b1\u03c5\u03c4\u03ae \u03b3\u03b9\u03b1 \u03c4\u03bf \u03c5\u03c0\u03cc\u03c3\u03c4\u03c1\u03c9\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03c0\u03b9\u03bf \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae, \u03b1\u03c6\u03bf\u03cd \u03b4\u03b5\u03bd \u03ba\u03b1\u03c4\u03b1\u03c4\u03bc\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03cc\u03bb\u03b5\u03c2 \u03bf\u03b9 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03b4\u03b9\u03b1\u03b8\u03ad\u03c4\u03bf\u03c5\u03bd \u03c4\u03b7 \u03b2\u03ad\u03bb\u03c4\u03b9\u03c3\u03c4\u03b7 \u03c4\u03b5\u03c4\u03c1\u03b1\u03c0\u03b5\u03c0\u03c4\u03b9\u03b4\u03b9\u03ba\u03ae \u03b1\u03bb\u03bb\u03b7\u03bb\u03bf\u03c5\u03c7\u03af\u03b1 P4-P3-P2-P1, \u03b3\u03b5\u03b3\u03bf\u03bd\u03cc\u03c2 \u03c0\u03bf\u03c5 \u03bf\u03b4\u03b7\u03b3\u03b5\u03af \u03c3\u03c4\u03b7\u03bd \u03c5\u03c0\u03bf\u03c8\u03af\u03b1, \u03cc\u03c4\u03b9 \u03c4\u03c1\u03b9\u03c4\u03bf\u03c4\u03b1\u03b3\u03ae \u03b4\u03bf\u03bc\u03b9\u03ba\u03ac \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03b3\u03bd\u03ce\u03c1\u03b9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c5\u03c0\u03bf\u03c3\u03c4\u03c1\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2. \u0395\u03c0\u03b9\u03c0\u03c1\u03cc\u03c3\u03b8\u03b5\u03c4\u03b1, \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b5\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2, \u03c5\u03c0\u03bf\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03cd\u03c0\u03b1\u03c1\u03be\u03b7 \u03ba\u03ac\u03c0\u03bf\u03b9\u03c9\u03bd \u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd, \u03bf\u03b9 \u03bf\u03c0\u03bf\u03af\u03b5\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c4\u03bc\u03bf\u03cd\u03bd \u03c4\u03b1 \u03c5\u03c0\u03bf\u03c3\u03c4\u03c1\u03ce\u03bc\u03b1\u03c4\u03ac \u03c4\u03bf\u03c5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03b3\u03bb\u03bf\u03c5\u03c4\u03b1\u03bc\u03b9\u03bd\u03b9\u03ba\u03cc \u03bf\u03be\u03cd <span style=\"color: #00ccff\"><span style=\"color: #000000\">(Glu)<\/span><sup id=\"cite_ref-10\" class=\"reference\"><a style=\"color: #00ccff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_note-10\">[10]<\/a><\/sup><\/span><\/li>\n<\/ol>\n<h3><span id=\".CE.95.CE.BD.CE.B5.CF.81.CE.B3.CE.BF.CF.80.CE.BF.CE.AF.CE.B7.CF.83.CE.B7_.CF.84.CF.89.CE.BD_.CE.BA.CE.B1.CF.83.CF.80.CE.B1.CF.83.CF.8E.CE.BD\"><\/span><span id=\"\u0395\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7_\u03c4\u03c9\u03bd_\u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd\" class=\"mw-headline\">\u0395\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd<\/span><span class=\"mw-editsection\" style=\"color: #00ccff\"><span class=\"mw-editsection-bracket\">[<\/span><a class=\"mw-editsection-visualeditor\" style=\"color: #00ccff\" title=\"\u0395\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03b5\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2: \u0395\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd\" href=\"https:\/\/el.wikipedia.org\/w\/index.php?title=%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82&amp;veaction=edit&amp;section=2\">\u0395\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1<\/a><span class=\"mw-editsection-divider\">\u00a0|\u00a0<\/span><a style=\"color: #00ccff\" title=\"\u0395\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03b5\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2: \u0395\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd\" href=\"https:\/\/el.wikipedia.org\/w\/index.php?title=%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82&amp;action=edit&amp;section=2\">\u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03ba\u03ce\u03b4\u03b9\u03ba\u03b1<\/a><span class=\"mw-editsection-bracket\">]<\/span><\/span><\/h3>\n<p>\u0394\u03cd\u03bf \u03ba\u03cd\u03c1\u03b9\u03b1 \u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03c4\u03b9\u03b1, \u03c0\u03bf\u03c5 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd \u03c4\u03b9\u03c2 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2, \u03ad\u03c7\u03bf\u03c5\u03bd \u03b5\u03bd\u03c4\u03bf\u03c0\u03b9\u03c3\u03c4\u03b5\u03af (\u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 2):<\/p>\n<ul>\n<li>\u03c4\u03bf \u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03c4\u03b9 \u03c4\u03c9\u03bd \u00ab<b>\u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd \u03b8\u03b1\u03bd\u03ac\u03c4\u03bf\u03c5<\/b>\u00bb (death receptor pathway) \u03ba\u03b1\u03b9<\/li>\n<li>\u03c4\u03bf\u00a0<b>\u03bc\u03b9\u03c4\u03bf\u03c7\u03bf\u03bd\u03b4\u03c1\u03b9\u03b1\u03ba\u03cc \u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03c4\u03b9<\/b>\u00a0(mitochondrial pathway)<span style=\"color: #00ccff\"><sup id=\"cite_ref-11\" class=\"reference\"><a style=\"color: #00ccff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_note-11\">[11]<\/a><\/sup><\/span>\u00a0.<\/li>\n<\/ul>\n<p>\u03a4\u03bf \u03c0\u03c1\u03ce\u03c4\u03bf, \u03be\u03b5\u03ba\u03b9\u03bd\u03ac \u03cc\u03c4\u03b1\u03bd \u03c3\u03c5\u03bd\u03b4\u03b5\u03b8\u03bf\u03cd\u03bd \u03b5\u03b9\u03b4\u03b9\u03ba\u03bf\u03af \u03c0\u03c1\u03bf\u03c3\u03b4\u03ad\u03c4\u03b5\u03c2, \u03c3\u03b5 \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03b5\u03af\u03c2 \u03c4\u03b7\u03c2\u00a0<a title=\"\u039a\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae \u03bc\u03b5\u03bc\u03b2\u03c1\u03ac\u03bd\u03b7\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CF%85%CF%84%CF%84%CE%B1%CF%81%CE%B9%CE%BA%CE%AE_%CE%BC%CE%B5%CE%BC%CE%B2%CF%81%CE%AC%CE%BD%CE%B7\"><u>\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae\u03c2 \u03bc\u03b5\u03bc\u03b2\u03c1\u03ac\u03bd\u03b7\u03c2<\/u><\/a>, \u03c0\u03bf\u03c5 \u03bf\u03bd\u03bf\u03bc\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u00ab\u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03b5\u03af\u03c2 \u03b8\u03b1\u03bd\u03ac\u03c4\u03bf\u03c5\u00bb \u03ae death receptors (DRs).\u00a0<span style=\"color: #00ccff\"><sup id=\"cite_ref-:1_12-0\" class=\"reference\"><a style=\"color: #00ccff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_note-:1-12\">[12]<\/a><\/sup><\/span><\/p>\n<p>\u03a4\u03bf \u03bc\u03b9\u03c4\u03bf\u03c7\u03bf\u03bd\u03b4\u03c1\u03b9\u03b1\u03ba\u03cc \u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03c4\u03b9 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2 \u03c4\u03c9\u03bd \u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd, \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03b5\u03af\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03bf \u03ba\u03b1\u03c4\u03b1\u03c4\u03bc\u03b7\u03bc\u03ad\u03bd\u03bf \u03b8\u03c1\u03b1\u03cd\u03c3\u03bc\u03b1 \u03c4\u03b7\u03c2\u00a0<span style=\"color: #00ccff\"><a style=\"color: #00ccff\" title=\"\u03a0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%A0%CF%81%CF%89%CF%84%CE%B5%CE%90%CE%BD%CE%B7\"><u>\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7\u03c2\u00a0<\/u><\/a><span style=\"color: #000000\">Bid<\/span>,<\/span> \u03b5\u03af\u03c4\u03b5 \u03b1\u03c0\u03cc \u03ac\u03bb\u03bb\u03b1 \u03c3\u03ae\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b1\u03c0\u03b5\u03bb\u03b5\u03c5\u03b8\u03ad\u03c1\u03c9\u03c3\u03b7 \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03ce\u03bd \u03c0\u03b5\u03c0\u03c4\u03b9\u03b4\u03af\u03c9\u03bd, \u03b1\u03c0\u03cc \u03c4\u03b1\u00a0<a title=\"\u039c\u03b9\u03c4\u03bf\u03c7\u03cc\u03bd\u03b4\u03c1\u03b9\u03bf\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9C%CE%B9%CF%84%CE%BF%CF%87%CF%8C%CE%BD%CE%B4%CF%81%CE%B9%CE%BF\"><u><span style=\"color: #00ccff\">\u03bc\u03b9\u03c4\u03bf\u03c7\u03cc\u03bd\u03b4\u03c1\u03b9\u03b1<\/span><\/u><\/a>. \u0388\u03bd\u03b1 \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03ac \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ad\u03b1\u03c2 \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03bd\u03af\u03c9\u03bd \u03ba\u03c5\u03c4\u03cc\u03c7\u03c1\u03c9\u03bc\u03b1 c. \u03a4\u03bf \u03ba\u03c5\u03c4\u03cc\u03c7\u03c1\u03c9\u03bc\u03b1 c \u03c3\u03c5\u03c3\u03c3\u03c9\u03c1\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03cc\u03c0\u03bb\u03b1\u03c3\u03bc\u03b1, \u03cc\u03c0\u03bf\u03c5 \u03b4\u03b5\u03c3\u03bc\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 Apaf-1 (apoptotic protease-activating factor-1), \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03ce\u03bd\u03c4\u03b1\u03c2 \u03b5\u03be\u03b1\u03c1\u03c4\u03ce\u03bc\u03b5\u03bd\u03b7 \u03b1\u03c0\u03cc\u00a0<a title=\"\u03a4\u03c1\u03b9\u03c6\u03c9\u03c3\u03c6\u03bf\u03c1\u03b9\u03ba\u03ae \u03b1\u03b4\u03b5\u03bd\u03bf\u03c3\u03af\u03bd\u03b7\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%A4%CF%81%CE%B9%CF%86%CF%89%CF%83%CF%86%CE%BF%CF%81%CE%B9%CE%BA%CE%AE_%CE%B1%CE%B4%CE%B5%CE%BD%CE%BF%CF%83%CE%AF%CE%BD%CE%B7\"><u><span style=\"color: #00ccff\">ATP<\/span><\/u><\/a>\u00a0(\u03ae dATP) \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03c4\u03b7\u03c2 \u03b4\u03b9\u03b1\u03bc\u03cc\u03c1\u03c6\u03c9\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 Apaf-1 \u03c0\u03bf\u03c5 \u03bf\u03b4\u03b7\u03b3\u03b5\u03af \u03c3\u03c4\u03bf\u03bd \u03bf\u03bb\u03b9\u03b3\u03bf\u03bc\u03b5\u03c1\u03b9\u03c3\u03bc\u03cc \u03c4\u03b7\u03c2. \u0397 \u03b4\u03ad\u03c3\u03bc\u03b5\u03c5\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03bf\u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b7\u03c2-9 \u03c3\u03c4\u03b1 \u03bf\u03bb\u03b9\u03b3\u03bf\u03bc\u03b5\u03c1\u03ae \u03c4\u03b7\u03c2 Apaf-1, \u03b4\u03b9\u03b1\u03bc\u03b5\u03c3\u03bf\u03bb\u03b1\u03b2\u03bf\u03cd\u03bc\u03b5\u03bd\u03b7 \u03b1\u03c0\u03cc \u03bf\u03bc\u03bf\u03c4\u03c5\u03c0\u03b9\u03ba\u03ad\u03c2 \u03b1\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ce\u03bd \u03c0\u03bf\u03c5 \u03ba\u03b1\u03bb\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u00ab\u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ad\u03c2 \u03c0\u03c1\u03bf\u03c3\u03ad\u03bb\u03ba\u03c5\u03c3\u03b7\u03c2 \u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd\u00bb [caspase recruitment domains (CARDs)], \u03ad\u03c7\u03bf\u03c5\u03bd \u03c9\u03c2 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c4\u03bf \u03c3\u03c7\u03b7\u03bc\u03b1\u03c4\u03b9\u03c3\u03bc\u03cc \u03b5\u03bd\u03cc\u03c2 \u03bc\u03b5\u03b3\u03b1\u03bb\u03bf\u03bc\u03bf\u03c1\u03b9\u03b1\u03ba\u03bf\u03cd \u03c3\u03c5\u03bc\u03c0\u03bb\u03cc\u03ba\u03bf\u03c5, \u03c0\u03bf\u03c5 \u03bf\u03bd\u03bf\u03bc\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9\u00a0<b>\u03b1\u03c0\u03bf\u03c0\u03c4\u03ce\u03c3\u03c9\u03bc\u03b1<\/b>\u00a0(apoptosome). \u0397 \u03b1\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03b1\u03c5\u03c4\u03ae \u03bc\u03b5\u03c4\u03b1\u03be\u03cd Apaf-1 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b7\u03c2-9 \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7\u03bd \u03b5\u03bd\u03b6\u03c5\u03bc\u03b9\u03ba\u03ae \u03b5\u03bd\u03b5\u03c1\u03b3\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03bf\u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b7\u03c2-9<span style=\"color: #00ccff\"><sup id=\"cite_ref-:1_12-1\" class=\"reference\"><a style=\"color: #00ccff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_note-:1-12\">[12]<\/a><\/sup><\/span><\/p>\n<h3><span id=\".CE.A5.CF.80.CE.BF.CF.83.CF.84.CF.81.CF.8E.CE.BC.CE.B1.CF.84.CE.B1_.CF.84.CF.89.CE.BD_.CE.BA.CE.B1.CF.83.CF.80.CE.B1.CF.83.CF.8E.CE.BD_.CE.BA.CE.B1.CF.84.CE.AC_.CF.84.CE.B7.CE.BD_.CE.B1.CF.80.CF.8C.CF.80.CF.84.CF.89.CF.83.CE.B7\"><\/span><span id=\"\u03a5\u03c0\u03bf\u03c3\u03c4\u03c1\u03ce\u03bc\u03b1\u03c4\u03b1_\u03c4\u03c9\u03bd_\u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd_\u03ba\u03b1\u03c4\u03ac_\u03c4\u03b7\u03bd_\u03b1\u03c0\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7\" class=\"mw-headline\">\u03a5\u03c0\u03bf\u03c3\u03c4\u03c1\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c4\u03c9\u03bd \u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03b1\u03c0\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7<\/span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[<\/span><span style=\"color: #00ccff\"><a class=\"mw-editsection-visualeditor\" style=\"color: #00ccff\" title=\"\u0395\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03b5\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2: \u03a5\u03c0\u03bf\u03c3\u03c4\u03c1\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c4\u03c9\u03bd \u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03b1\u03c0\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7\" href=\"https:\/\/el.wikipedia.org\/w\/index.php?title=%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82&amp;veaction=edit&amp;section=3\">\u0395\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1<\/a><span class=\"mw-editsection-divider\">\u00a0|\u00a0<\/span><a style=\"color: #00ccff\" title=\"\u0395\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03b5\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2: \u03a5\u03c0\u03bf\u03c3\u03c4\u03c1\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c4\u03c9\u03bd \u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03b1\u03c0\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7\" href=\"https:\/\/el.wikipedia.org\/w\/index.php?title=%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82&amp;action=edit&amp;section=3\">\u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03ba\u03ce\u03b4\u03b9\u03ba\u03b1<\/a><span class=\"mw-editsection-bracket\">]<\/span><\/span><\/span><\/h3>\n<p>\u03a4\u03bf 1998 \u03b4\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b9 65 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b5\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c4\u03bc\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c0\u03c1\u03c9\u03c4\u03b5\u03ac\u03c3\u03b5\u03c2 \u03c4\u03b7\u03c2 \u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 \u03c4\u03c9\u03bd \u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd<span style=\"color: #00ccff\"><sup id=\"cite_ref-13\" class=\"reference\"><a style=\"color: #00ccff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_note-13\">[13]<\/a><\/sup><\/span>\u03a4\u03b1 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03b3\u03bd\u03c9\u03c3\u03c4\u03ac \u03c9\u03c2 \u03c4\u03cc\u03c4\u03b5 \u03c5\u03c0\u03bf\u03c3\u03c4\u03c1\u03ce\u03bc\u03b1\u03c4\u03b1, \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03c3\u03b1\u03bd \u03bd\u03b1 \u03ba\u03b1\u03c4\u03b7\u03b3\u03bf\u03c1\u03b9\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03bf\u03cd\u03bd \u03c3\u03b5 \u03bc\u03b9\u03ba\u03c1\u03cc \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ce\u03bd \u03bf\u03bc\u03ac\u03b4\u03c9\u03bd, \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03bc\u03c0\u03bb\u03ad\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03c3\u03c4\u03ae\u03c1\u03b9\u03be\u03b7 \u03c4\u03bf\u03c5\u00a0<span style=\"color: #00ccff\"><a style=\"color: #00ccff\" title=\"\u039a\u03c5\u03c4\u03c4\u03b1\u03c1\u03cc\u03c0\u03bb\u03b1\u03c3\u03bc\u03b1\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CF%85%CF%84%CF%84%CE%B1%CF%81%CF%8C%CF%80%CE%BB%CE%B1%CF%83%CE%BC%CE%B1\"><u>\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03bf\u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2<\/u><\/a>\u00a0<\/span>\u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5\u00a0<span style=\"color: #00ccff\"><a style=\"color: #00ccff\" title=\"\u039a\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03cc\u03c2 \u03c0\u03c5\u03c1\u03ae\u03bd\u03b1\u03c2\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CF%85%CF%84%CF%84%CE%B1%CF%81%CE%B9%CE%BA%CF%8C%CF%82_%CF%80%CF%85%CF%81%CE%AE%CE%BD%CE%B1%CF%82\"><u>\u03c0\u03c5\u03c1\u03ae\u03bd\u03b1<\/u><\/a>,<\/span> \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03bc\u03c0\u03bb\u03ad\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03bc\u03b5\u03c4\u03b1\u03b3\u03c9\u03b3\u03ae \u03c3\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03c1\u03cd\u03b8\u03bc\u03b9\u03c3\u03b7 \u03c4\u03b7\u03c2\u00a0<a title=\"\u039c\u03b5\u03c4\u03b1\u03b3\u03c1\u03b1\u03c6\u03ae (\u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1)\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9C%CE%B5%CF%84%CE%B1%CE%B3%CF%81%CE%B1%CF%86%CE%AE_(%CE%B2%CE%B9%CE%BF%CE%BB%CE%BF%CE%B3%CE%AF%CE%B1)\"><u>\u03bc\u03b5\u03c4\u03b1\u03b3\u03c1\u03b1\u03c6\u03ae\u03c2<\/u><\/a>, \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b5\u03c2 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03c4\u03ad\u03c2 \u03c4\u03bf\u03c5\u00a0<span style=\"color: #00ccff\"><a style=\"color: #00ccff\" title=\"\u039a\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03cc\u03c2 \u03ba\u03cd\u03ba\u03bb\u03bf\u03c2\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CF%85%CF%84%CF%84%CE%B1%CF%81%CE%B9%CE%BA%CF%8C%CF%82_%CE%BA%CF%8D%CE%BA%CE%BB%CE%BF%CF%82\"><u>\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03bf\u03cd \u03ba\u03cd\u03ba\u03bb\u03bf\u03c5<\/u><\/a><\/span>\u00a0\u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b9 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03bc\u03c0\u03bb\u03ad\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03c4\u03b9\u03b3\u03c1\u03b1\u03c6\u03ae \u03c4\u03bf\u03c5 DNA \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03b4\u03b9\u03cc\u03c1\u03b8\u03c9\u03c3\u03b7 \u03b2\u03bb\u03b1\u03b2\u03ce\u03bd \u03c4\u03bf\u03c5. \u0391\u03c0\u03cc \u03c4\u03cc\u03c4\u03b5, \u03bf \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc\u03c2 \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03c3\u03c4\u03c1\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03c4\u03c9\u03bd \u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd \u03ad\u03c7\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03b1\u03c5\u03be\u03b7\u03b8\u03b5\u03af, \u03c6\u03b8\u03ac\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03bf 2003 \u03c3\u03c4\u03b7\u03bd \u03c4\u03b1\u03c5\u03c4\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 280 \u03c0\u03c1\u03c9\u03c4\u03b5\u03ca\u03bd\u03ce\u03bd &#8211; \u03c3\u03c4\u03cc\u03c7\u03c9\u03bd \u03c4\u03c9\u03bd \u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd<sup id=\"cite_ref-14\" class=\"reference\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_note-14\"><span style=\"color: #00ccff\">[14]<\/span><\/a><\/sup>\u039f\u03b9 \u03c0\u03c1\u03bf- \u03ba\u03b1\u03b9 \u03b1\u03bd\u03c4\u03b9-\u03b1\u03c0\u03bf\u03c0\u03c4\u03c9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b5\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03bd \u03bf\u03b9 \u03c0\u03c1\u03ce\u03c4\u03bf\u03b9 \u03c3\u03c4\u03cc\u03c7\u03bf\u03b9 \u03c4\u03c9\u03bd \u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03ad\u03bd\u03b1 \u03b1\u03c0\u03bf\u03c0\u03c4\u03c9\u03c4\u03b9\u03ba\u03cc \u03b5\u03c1\u03ad\u03b8\u03b9\u03c3\u03bc\u03b1<span style=\"color: #00ccff\"><sup id=\"cite_ref-15\" class=\"reference\"><a style=\"color: #00ccff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_note-15\">[15]<\/a><\/sup><\/span>\u039a\u03b1\u03b8\u03ce\u03c2 \u03c4\u03bf \u03b1\u03c0\u03bf\u03c0\u03c4\u03c9\u03c4\u03b9\u03ba\u03cc \u03c3\u03ae\u03bc\u03b1 \u03b4\u03b9\u03b1\u03b4\u03af\u03b4\u03b5\u03c4\u03b1\u03b9, \u03bf\u03b9 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd \u03ac\u03bb\u03bb\u03b1 \u03c3\u03c5\u03c3\u03c4\u03b1\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7\u03c2 \u03b1\u03c0\u03bf\u03c0\u03c4\u03c9\u03c4\u03b9\u03ba\u03ae\u03c2 \u03bc\u03b7\u03c7\u03b1\u03bd\u03ae\u03c2.\u039f\u03b9 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c4\u03bc\u03bf\u03cd\u03bd \u03b4\u03bf\u03bc\u03b9\u03ba\u03ad\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03c5\u03c1\u03ae\u03bd\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03bf\u03c3\u03ba\u03b5\u03bb\u03b5\u03c4\u03bf\u03cd. \u0397 \u03c0\u03c1\u03c9\u03c4\u03b5\u03cc\u03bb\u03c5\u03c3\u03b7 \u03c4\u03c9\u03bd \u03bb\u03b1\u03bc\u03b9\u03bd\u03ce\u03bd (lamins), \u03c4\u03b7\u03c2 NuMa, \u03c4\u03b7\u03c2 SAF-A \u03ba\u03b9 \u03ac\u03bb\u03bb\u03c9\u03bd, \u03b5\u03c0\u03ac\u03b3\u03bf\u03c5\u03bd \u03c4\u03b7 \u03b4\u03b9\u03ac\u03bb\u03c5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c0\u03c5\u03c1\u03ae\u03bd\u03b1. \u039f\u03bc\u03bf\u03af\u03c9\u03c2, \u03bf\u03b9 \u03ba\u03b1\u03c3\u03c0\u03ac\u03c3\u03b5\u03c2 \u03b4\u03b9\u03b1\u03c1\u03c1\u03b7\u03b3\u03bd\u03cd\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b1\u03ba\u03b5\u03c1\u03b1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03bf\u03c5\u00a0<span style=\"color: #00ccff\"><a style=\"color: #00ccff\" title=\"\u039a\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03cc\u03c2 \u03c3\u03ba\u03b5\u03bb\u03b5\u03c4\u03cc\u03c2\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CF%85%CF%84%CF%84%CE%B1%CF%81%CE%B9%CE%BA%CF%8C%CF%82_%CF%83%CE%BA%CE%B5%CE%BB%CE%B5%CF%84%CF%8C%CF%82\"><u>\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03bf\u03c3\u03ba\u03b5\u03bb\u03b5\u03c4\u03bf\u03cd<\/u><\/a><\/span>\u00a0\u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03c1\u03c9\u03c4\u03b5\u03cc\u03bb\u03c5\u03c3\u03b7 \u03c4\u03c9\u03bd \u03c0\u03c1\u03c9\u03c4\u03b5\u03ca\u03bd\u03ce\u03bd \u03cc\u03c0\u03c9\u03c2 \u03b7 \u03c6\u03bf\u03b4\u03c1\u03af\u03bd\u03b7 (fodrin),\u03b7 Gas2, \u03bf\u03b9 \u03ba\u03b5\u03c1\u03b1\u03c4\u03af\u03bd\u03b5\u03c2 (keratins), \u03b7 Rabaptin-5 \u03ba\u03b1\u03b9 \u03b7 \u03b1\u03ba\u03c4\u03af\u03bd\u03b7. \u0397 \u03ba\u03b1\u03c4\u03ac\u03c4\u03bc\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b2-\u03ba\u03b1\u03c4\u03b5\u03bd\u03af\u03bd\u03b7\u03c2 (\u03b2-catenin) \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 FAK, \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03b4\u03b9\u03b1\u03ba\u03cc\u03c0\u03c4\u03b5\u03b9 \u03c4\u03b9\u03c2 \u03c3\u03c5\u03bd\u03b4\u03ad\u03c3\u03b5\u03b9\u03c2 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b5\u03c3\u03c4\u03b9\u03b1\u03ba\u03ae \u03c0\u03c1\u03bf\u03c3\u03ba\u03cc\u03bb\u03bb\u03b7\u03c3\u03b7 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd \u03ba\u03b1\u03b9 \u03b8\u03b5\u03bc\u03ad\u03bb\u03b9\u03b1\u03c2 \u03bf\u03c5\u03c3\u03af\u03b1\u03c2. \u039c\u03b1\u03b6\u03af, \u03bf\u03b9 \u03ba\u03b1\u03c4\u03b1\u03c4\u03bc\u03ae\u03c3\u03b5\u03b9\u03c2 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03b5\u03bd\u03b4\u03b5\u03c7\u03bf\u03bc\u03ad\u03bd\u03c9\u03c2 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03bf\u03cd\u03bd \u03c4\u03bf \u00ab\u03c0\u03b1\u03ba\u03b5\u03c4\u03ac\u03c1\u03b9\u03c3\u03bc\u03b1\u00bb \u03c4\u03bf\u03c5 \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03b4\u03b9\u03b5\u03c5\u03ba\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03c4\u03b7\u03c2\u00a0<span style=\"color: #00ccff\"><a style=\"color: #00ccff\" title=\"\u03a6\u03b1\u03b3\u03bf\u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03c3\u03b7\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%A6%CE%B1%CE%B3%CE%BF%CE%BA%CF%85%CF%84%CF%84%CE%AC%CF%81%CF%89%CF%83%CE%B7\"><u>\u03c6\u03b1\u03b3\u03bf\u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03c3\u03b7\u03c2<\/u><\/a><\/span>\u00a0\u03c0\u03bf\u03c5 \u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af \u03c3\u03c4\u03b7 \u03c3\u03c5\u03bd\u03ad\u03c7\u03b5\u03b9\u03b1.<span style=\"color: #00ccff\"><sup id=\"cite_ref-16\" class=\"reference\"><a style=\"color: #00ccff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_note-16\">[16]<\/a><\/sup><sup id=\"cite_ref-17\" class=\"reference\"><a style=\"color: #00ccff\" href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_note-17\">[17]<\/a><\/sup><\/span><\/p>\n<div class=\"thumb tright\">\n<div class=\"thumbinner\">\n<p><a class=\"image\" href=\"https:\/\/commons.wikimedia.org\/wiki\/File:1-s2.0-S0962892401021730-gr1_(2).jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"thumbimage\" src=\"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/e\/e3\/1-s2.0-S0962892401021730-gr1_%282%29.jpg\/220px-1-s2.0-S0962892401021730-gr1_%282%29.jpg\" alt=\"\" width=\"220\" height=\"128\" \/><\/a><\/p>\n<div class=\"thumbcaption\">\n<div class=\"magnify\"><\/div>\n<p><em><strong>\u0395\u03b9\u03ba. 2<\/strong>.\u00a0<b>\u03a0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03ac \u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03c4\u03b9\u03b1 \u03c3\u03c4\u03b7\u03bd \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03ba\u03b1\u03c3\u03c0\u03b1\u03c3\u03ce\u03bd<\/b>. \u03a4\u03bf \u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03c4\u03b9 \u03c4\u03c9\u03bd \u00ab\u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd \u03b8\u03b1\u03bd\u03ac\u03c4\u03bf\u03c5\u00bb (death receptor) (\u03b1\u03c1\u03b9\u03c3\u03c4\u03b5\u03c1\u03cc \u03bc\u03b9\u03c3\u03cc \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1\u03c2), \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03c3\u03b4\u03b5\u03c3\u03b7 \u03b5\u03bd\u03cc\u03c2 \u03c3\u03c5\u03bd\u03b4\u03ad\u03c4\u03b7 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03b5\u03af\u03c2.<\/em><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"mw-references-wrap mw-references-columns\">\n<ol class=\"references\">\n<li id=\"cite_note-1\"><span class=\"mw-cite-backlink\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_ref-1\"><span class=\"cite-accessibility-label\">\u0386\u03bb\u03bc\u03b1 \u03c0\u03ac\u03bd\u03c9<\/span>\u2191<\/a><\/span>\u00a0<span class=\"reference-text\"><span class=\"citation web\"><a class=\"external text\" href=\"http:\/\/panacea.med.uoa.gr\/topic.aspx?id=324\" rel=\"nofollow\">\u00ab\u03a4\u03b1 \u03ad\u03bd\u03b6\u03c5\u03bc\u03b1 \u03c4\u03b7\u03c2 \u03b1\u03c0\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7\u03c2\u00bb<\/a>.\u00a0<i>\u0397\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03bd\u03b9\u03ba\u03ae \u03a0\u03cd\u03bb\u03b7 \u03c4\u03bf\u03c5 \u0391\u03c3\u03ba\u03bb\u03b7\u03c0\u03b9\u03b1\u03ba\u03bf\u03cd \u03a0\u03ac\u03c1\u03ba\u03bf\u03c5<\/i><span class=\"reference-accessdate\">. \u0391\u03bd\u03b1\u03ba\u03c4\u03ae\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03b9\u03c2 2018-5-12<\/span>.<\/span><\/span><\/li>\n<li id=\"cite_note-2\"><span class=\"mw-cite-backlink\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_ref-2\"><span class=\"cite-accessibility-label\">\u0386\u03bb\u03bc\u03b1 \u03c0\u03ac\u03bd\u03c9<\/span>\u2191<\/a><\/span>\u00a0<span class=\"reference-text\"><span class=\"citation Journal\">Cerretti, D. P.; Kozlosky, C. J.; Mosley, B.; Nelson, N.; Ness, K. Van; Greenstreet, T. A.; March, C. J.; Kronheim\u00a0<i>\u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03bf\u03b9<\/i>. (1992-04-03).\u00a0<a class=\"external text\" href=\"http:\/\/science.sciencemag.org\/content\/256\/5053\/97\" rel=\"nofollow\">\u00abMolecular cloning of the interleukin-1 beta converting enzyme\u00bb<\/a>\u00a0(\u03c3\u03c4\u03b1 \u03b1\u03b3\u03b3\u03bb\u03b9\u03ba\u03ac).\u00a0<i>Science<\/i>\u00a0<b>256<\/b>\u00a0(5053): 97\u2013100.\u00a0<a class=\"mw-redirect\" title=\"Digital object identifier\" href=\"https:\/\/el.wikipedia.org\/wiki\/Digital_object_identifier\">doi<\/a>:<span class=\"neverexpand\"><a class=\"external text\" href=\"http:\/\/dx.doi.org\/10.1126%2Fscience.1373520\" rel=\"nofollow\">10.1126\/science.1373520<\/a><\/span>.\u00a0<a title=\"International Standard Serial Number\" href=\"https:\/\/el.wikipedia.org\/wiki\/International_Standard_Serial_Number\">ISSN<\/a>\u00a0<a class=\"external text\" href=\"http:\/\/worldcat.org\/issn\/0036-8075\" rel=\"nofollow\">0036-8075<\/a>.\u00a0<a title=\"PubMed Identifier\" href=\"https:\/\/el.wikipedia.org\/wiki\/PubMed_Identifier\">PMID<\/a>\u00a0<a class=\"external text\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/1373520\" rel=\"nofollow\">1373520<\/a>.<\/span><\/span><\/li>\n<li id=\"cite_note-:0-3\"><span class=\"mw-cite-backlink\">\u2191\u00a0<sup><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_ref-:0_3-0\"><span class=\"cite-accessibility-label\">\u0386\u03bb\u03bc\u03b1 \u03c0\u03ac\u03bd\u03c9, \u03c3\u03c4\u03bf:<\/span>3,0<\/a><\/sup>\u00a0<sup><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_ref-:0_3-1\">3,1<\/a><\/sup><\/span>\u00a0<span class=\"reference-text\"><span class=\"citation Journal\"><a class=\"external text\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0163725801001590\" rel=\"nofollow\">\u00abThe machinery of programmed cell death\u00bb<\/a>\u00a0(\u03c3\u03c4\u03b1 \u03b1\u03b3\u03b3\u03bb\u03b9\u03ba\u03ac).\u00a0<i>Pharmacology &amp; Therapeutics<\/i>\u00a0<b>92<\/b>\u00a0(1): 57\u201370. 2001-10-01.\u00a0<a class=\"mw-redirect\" title=\"Digital object identifier\" href=\"https:\/\/el.wikipedia.org\/wiki\/Digital_object_identifier\">doi<\/a>:<span class=\"neverexpand\"><a class=\"external text\" href=\"http:\/\/dx.doi.org\/10.1016%2FS0163-7258%2801%2900159-0\" rel=\"nofollow\">10.1016\/S0163-7258(01)00159-0<\/a><\/span>.\u00a0<a title=\"International Standard Serial Number\" href=\"https:\/\/el.wikipedia.org\/wiki\/International_Standard_Serial_Number\">ISSN<\/a><a class=\"external text\" href=\"http:\/\/worldcat.org\/issn\/0163-7258\" rel=\"nofollow\">0163-7258<\/a>.<\/span><\/span><\/li>\n<li id=\"cite_note-4\"><span class=\"mw-cite-backlink\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_ref-4\"><span class=\"cite-accessibility-label\">\u0386\u03bb\u03bc\u03b1 \u03c0\u03ac\u03bd\u03c9<\/span>\u2191<\/a><\/span>\u00a0<span class=\"reference-text\"><span class=\"citation Journal\"><a class=\"external text\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0167483898001332\" rel=\"nofollow\">\u00abProperties of the caspases\u00bb<\/a>\u00a0(\u03c3\u03c4\u03b1 \u03b1\u03b3\u03b3\u03bb\u03b9\u03ba\u03ac).\u00a0<i>Biochimica et Biophysica Acta (BBA) &#8211; Protein Structure and Molecular Enzymology<\/i>\u00a0<b>1387<\/b>\u00a0(1-2): 17\u201331. 1998-09-08.\u00a0<a class=\"mw-redirect\" title=\"Digital object identifier\" href=\"https:\/\/el.wikipedia.org\/wiki\/Digital_object_identifier\">doi<\/a>:<span class=\"neverexpand\"><a class=\"external text\" href=\"http:\/\/dx.doi.org\/10.1016%2FS0167-4838%2898%2900133-2\" rel=\"nofollow\">10.1016\/S0167-4838(98)00133-2<\/a><\/span>.\u00a0<a title=\"International Standard Serial Number\" href=\"https:\/\/el.wikipedia.org\/wiki\/International_Standard_Serial_Number\">ISSN<\/a>\u00a0<a class=\"external text\" href=\"http:\/\/worldcat.org\/issn\/0167-4838\" rel=\"nofollow\">0167-4838<\/a>.<\/span><\/span><\/li>\n<li id=\"cite_note-5\"><span class=\"mw-cite-backlink\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_ref-5\"><span class=\"cite-accessibility-label\">\u0386\u03bb\u03bc\u03b1 \u03c0\u03ac\u03bd\u03c9<\/span>\u2191<\/a><\/span>\u00a0<span class=\"reference-text\"><span class=\"citation Journal\"><a class=\"external text\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0968000497010438\" rel=\"nofollow\">\u00abThe CARD domain: a new apoptotic signalling motif\u00bb<\/a>\u00a0(\u03c3\u03c4\u03b1 \u03b1\u03b3\u03b3\u03bb\u03b9\u03ba\u03ac).\u00a0<i>Trends in Biochemical Sciences<\/i>\u00a0<b>22<\/b>\u00a0(5): 155\u2013156. 1997-05-01.\u00a0<a class=\"mw-redirect\" title=\"Digital object identifier\" href=\"https:\/\/el.wikipedia.org\/wiki\/Digital_object_identifier\">doi<\/a>:<span class=\"neverexpand\"><a class=\"external text\" href=\"http:\/\/dx.doi.org\/10.1016%2FS0968-0004%2897%2901043-8\" rel=\"nofollow\">10.1016\/S0968-0004(97)01043-8<\/a><\/span>.\u00a0<a title=\"International Standard Serial Number\" href=\"https:\/\/el.wikipedia.org\/wiki\/International_Standard_Serial_Number\">ISSN<\/a>\u00a0<a class=\"external text\" href=\"http:\/\/worldcat.org\/issn\/0968-0004\" rel=\"nofollow\">0968-0004<\/a>.<\/span><\/span><\/li>\n<li id=\"cite_note-6\"><span class=\"mw-cite-backlink\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_ref-6\"><span class=\"cite-accessibility-label\">\u0386\u03bb\u03bc\u03b1 \u03c0\u03ac\u03bd\u03c9<\/span>\u2191<\/a><\/span>\u00a0<span class=\"reference-text\"><span class=\"citation Journal\"><a class=\"external text\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1097276502004823\" rel=\"nofollow\">\u00abMechanisms of Caspase Activation and Inhibition during Apoptosis\u00bb<\/a>\u00a0(\u03c3\u03c4\u03b1 \u03b1\u03b3\u03b3\u03bb\u03b9\u03ba\u03ac).\u00a0<i>Molecular Cell<\/i>\u00a0<b>9<\/b>\u00a0(3): 459\u2013470. 2002-03-01.\u00a0<a class=\"mw-redirect\" title=\"Digital object identifier\" href=\"https:\/\/el.wikipedia.org\/wiki\/Digital_object_identifier\">doi<\/a>:<span class=\"neverexpand\"><a class=\"external text\" href=\"http:\/\/dx.doi.org\/10.1016%2FS1097-2765%2802%2900482-3\" rel=\"nofollow\">10.1016\/S1097-2765(02)00482-3<\/a><\/span>.\u00a0<a title=\"International Standard Serial Number\" href=\"https:\/\/el.wikipedia.org\/wiki\/International_Standard_Serial_Number\">ISSN<\/a>\u00a0<a class=\"external text\" href=\"http:\/\/worldcat.org\/issn\/1097-2765\" rel=\"nofollow\">1097-2765<\/a>.<\/span><\/span><\/li>\n<li id=\"cite_note-7\"><span class=\"mw-cite-backlink\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_ref-7\"><span class=\"cite-accessibility-label\">\u0386\u03bb\u03bc\u03b1 \u03c0\u03ac\u03bd\u03c9<\/span>\u2191<\/a><\/span>\u00a0<span class=\"reference-text\"><span class=\"citation Journal\">Thornberry, Nancy A.; Rano, Thomas A.; Peterson, Erin P.; Rasper, Dita M.; Timkey, Tracy; Garcia-Calvo, Margarita; Houtzager, Vicky M.; Nordstrom, Penny A.\u00a0<i>\u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03bf\u03b9<\/i>. (1997-07-18).\u00a0<a class=\"external text\" href=\"http:\/\/www.jbc.org\/content\/272\/29\/17907\" rel=\"nofollow\">\u00abA Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B FUNCTIONAL RELATIONSHIPS ESTABLISHED FOR KEY MEDIATORS OF APOPTOSIS\u00bb<\/a>\u00a0(\u03c3\u03c4\u03b1 \u03b1\u03b3\u03b3\u03bb\u03b9\u03ba\u03ac).\u00a0<i>Journal of Biological Chemistry<\/i>\u00a0<b>272<\/b>\u00a0(29): 17907\u201317911.\u00a0<a class=\"mw-redirect\" title=\"Digital object identifier\" href=\"https:\/\/el.wikipedia.org\/wiki\/Digital_object_identifier\">doi<\/a>:<span class=\"neverexpand\"><a class=\"external text\" href=\"http:\/\/dx.doi.org\/10.1074%2Fjbc.272.29.17907\" rel=\"nofollow\">10.1074\/jbc.272.29.17907<\/a><\/span>.\u00a0<a title=\"International Standard Serial Number\" href=\"https:\/\/el.wikipedia.org\/wiki\/International_Standard_Serial_Number\">ISSN<\/a>\u00a0<a class=\"external text\" href=\"http:\/\/worldcat.org\/issn\/0021-9258\" rel=\"nofollow\">0021-9258<\/a>.\u00a0<a title=\"PubMed Identifier\" href=\"https:\/\/el.wikipedia.org\/wiki\/PubMed_Identifier\">PMID<\/a>\u00a0<a class=\"external text\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9218414\" rel=\"nofollow\">9218414<\/a>.<\/span><\/span><\/li>\n<li id=\"cite_note-8\"><span class=\"mw-cite-backlink\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_ref-8\"><span class=\"cite-accessibility-label\">\u0386\u03bb\u03bc\u03b1 \u03c0\u03ac\u03bd\u03c9<\/span>\u2191<\/a><\/span>\u00a0<span class=\"reference-text\"><span class=\"citation Journal\">Van de Craen, Marc; Vandenabeele, Peter; Declercq, Wim; Van den Brande, Ilse; Van Loo, Geert; Molemans, Francis; Schotte, Peter; Van Criekinge, Wim\u00a0<i>\u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03bf\u03b9<\/i>. (1997-02-10).\u00a0<a class=\"external text\" href=\"https:\/\/febs.onlinelibrary.wiley.com\/doi\/abs\/10.1016\/S0014-5793(97)00026-4\" rel=\"nofollow\">\u00abCharacterization of seven murine caspase family members\u00bb<\/a>\u00a0(\u03c3\u03c4\u03b1 \u03b1\u03b3\u03b3\u03bb\u03b9\u03ba\u03ac).\u00a0<i>FEBS Letters<\/i>\u00a0<b>403<\/b>\u00a0(1): 61\u201369.\u00a0<a class=\"mw-redirect\" title=\"Digital object identifier\" href=\"https:\/\/el.wikipedia.org\/wiki\/Digital_object_identifier\">doi<\/a>:<span class=\"neverexpand\"><a class=\"external text\" href=\"http:\/\/dx.doi.org\/10.1016%2Fs0014-5793%2897%2900026-4\" rel=\"nofollow\">10.1016\/s0014-5793(97)00026-4<\/a><\/span>.\u00a0<a title=\"International Standard Serial Number\" href=\"https:\/\/el.wikipedia.org\/wiki\/International_Standard_Serial_Number\">ISSN<\/a>\u00a0<a class=\"external text\" href=\"http:\/\/worldcat.org\/issn\/0014-5793\" rel=\"nofollow\">0014-5793<\/a>.<\/span><\/span><\/li>\n<li id=\"cite_note-9\"><span class=\"mw-cite-backlink\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_ref-9\"><span class=\"cite-accessibility-label\">\u0386\u03bb\u03bc\u03b1 \u03c0\u03ac\u03bd\u03c9<\/span>\u2191<\/a><\/span>\u00a0<span class=\"reference-text\"><span class=\"citation Journal\">Mittl, Peer R. E.; Marco, Stefania Di; Krebs, Joseph F.; Bai, Xu; Karanewsky, Donald S.; Priestle, John P.; Tomaselli, Kevin J.; Gr\u00fctter, Markus G. (1997-03-07).\u00a0<a class=\"external text\" href=\"http:\/\/www.jbc.org\/content\/272\/10\/6539\" rel=\"nofollow\">\u00abStructure of Recombinant Human CPP32 in Complex with the Tetrapeptide Acetyl-Asp-Val-Ala-Asp Fluoromethyl Ketone\u00bb<\/a>\u00a0(\u03c3\u03c4\u03b1 \u03b1\u03b3\u03b3\u03bb\u03b9\u03ba\u03ac).\u00a0<i>Journal of Biological Chemistry<\/i>\u00a0<b>272<\/b>\u00a0(10): 6539\u20136547.\u00a0<a class=\"mw-redirect\" title=\"Digital object identifier\" href=\"https:\/\/el.wikipedia.org\/wiki\/Digital_object_identifier\">doi<\/a>:<span class=\"neverexpand\"><a class=\"external text\" href=\"http:\/\/dx.doi.org\/10.1074%2Fjbc.272.10.6539\" rel=\"nofollow\">10.1074\/jbc.272.10.6539<\/a><\/span>.\u00a0<a title=\"International Standard Serial Number\" href=\"https:\/\/el.wikipedia.org\/wiki\/International_Standard_Serial_Number\">ISSN<\/a>\u00a0<a class=\"external text\" href=\"http:\/\/worldcat.org\/issn\/0021-9258\" rel=\"nofollow\">0021-9258<\/a>.\u00a0<a title=\"PubMed Identifier\" href=\"https:\/\/el.wikipedia.org\/wiki\/PubMed_Identifier\">PMID<\/a>\u00a0<a class=\"external text\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9045680\" rel=\"nofollow\">9045680<\/a>.<\/span><\/span><\/li>\n<li id=\"cite_note-10\"><span class=\"mw-cite-backlink\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_ref-10\"><span class=\"cite-accessibility-label\">\u0386\u03bb\u03bc\u03b1 \u03c0\u03ac\u03bd\u03c9<\/span>\u2191<\/a><\/span>\u00a0<span class=\"reference-text\"><span class=\"citation Journal\"><a class=\"external text\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0925477305000559\" rel=\"nofollow\">\u00abThe Drosophila caspase DRONC is required for metamorphosis and cell death in response to irradiation and developmental signals\u00bb<\/a>\u00a0(\u03c3\u03c4\u03b1 \u03b1\u03b3\u03b3\u03bb\u03b9\u03ba\u03ac).\u00a0<i>Mechanisms of Development<\/i>\u00a0<b>122<\/b>\u00a0(7-8): 914\u2013927. 2005-07-01.\u00a0<a class=\"mw-redirect\" title=\"Digital object identifier\" href=\"https:\/\/el.wikipedia.org\/wiki\/Digital_object_identifier\">doi<\/a>:<span class=\"neverexpand\"><a class=\"external text\" href=\"http:\/\/dx.doi.org\/10.1016%2Fj.mod.2005.04.003\" rel=\"nofollow\">10.1016\/j.mod.2005.04.003<\/a><\/span>.\u00a0<a title=\"International Standard Serial Number\" href=\"https:\/\/el.wikipedia.org\/wiki\/International_Standard_Serial_Number\">ISSN<\/a><a class=\"external text\" href=\"http:\/\/worldcat.org\/issn\/0925-4773\" rel=\"nofollow\">0925-4773<\/a>.<\/span><\/span><\/li>\n<li id=\"cite_note-11\"><span class=\"mw-cite-backlink\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_ref-11\"><span class=\"cite-accessibility-label\">\u0386\u03bb\u03bc\u03b1 \u03c0\u03ac\u03bd\u03c9<\/span>\u2191<\/a><\/span>\u00a0<span class=\"reference-text\"><span class=\"citation Journal\">William C. Earnshaw; Luis M. Martins; Kaufmann, Scott H. (1999).\u00a0<a class=\"external text\" href=\"https:\/\/doi.org\/10.1146\/annurev.biochem.68.1.383\" rel=\"nofollow\">\u00abMammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis\u00bb<\/a>.\u00a0<i>Annual Review of Biochemistry<\/i>\u00a0<b>68<\/b>\u00a0(1): 383\u2013424.\u00a0<a class=\"mw-redirect\" title=\"Digital object identifier\" href=\"https:\/\/el.wikipedia.org\/wiki\/Digital_object_identifier\">doi<\/a>:<span class=\"neverexpand\"><a class=\"external text\" href=\"http:\/\/dx.doi.org\/10.1146%2Fannurev.biochem.68.1.383\" rel=\"nofollow\">10.1146\/annurev.biochem.68.1.383<\/a><\/span>.\u00a0<a title=\"PubMed Identifier\" href=\"https:\/\/el.wikipedia.org\/wiki\/PubMed_Identifier\">PMID<\/a>\u00a0<a class=\"external text\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10872455\" rel=\"nofollow\">10872455<\/a>.<\/span><\/span><\/li>\n<li id=\"cite_note-:1-12\"><span class=\"mw-cite-backlink\">\u2191\u00a0<sup><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_ref-:1_12-0\"><span class=\"cite-accessibility-label\">\u0386\u03bb\u03bc\u03b1 \u03c0\u03ac\u03bd\u03c9, \u03c3\u03c4\u03bf:<\/span>12,0<\/a><\/sup>\u00a0<sup><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_ref-:1_12-1\">12,1<\/a><\/sup><\/span>\u00a0<span class=\"reference-text\"><span class=\"citation Journal\"><a class=\"external text\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0955067499800349\" rel=\"nofollow\">\u00abApoptosis control by death and decoy receptors\u00bb<\/a>\u00a0(\u03c3\u03c4\u03b1 \u03b1\u03b3\u03b3\u03bb\u03b9\u03ba\u03ac).\u00a0<i>Current Opinion in Cell Biology<\/i>\u00a0<b>11<\/b>\u00a0(2): 255\u2013260. 1999-04-01.\u00a0<a class=\"mw-redirect\" title=\"Digital object identifier\" href=\"https:\/\/el.wikipedia.org\/wiki\/Digital_object_identifier\">doi<\/a>:<span class=\"neverexpand\"><a class=\"external text\" href=\"http:\/\/dx.doi.org\/10.1016%2FS0955-0674%2899%2980034-9\" rel=\"nofollow\">10.1016\/S0955-0674(99)80034-9<\/a><\/span>.\u00a0<a title=\"International Standard Serial Number\" href=\"https:\/\/el.wikipedia.org\/wiki\/International_Standard_Serial_Number\">ISSN<\/a>\u00a0<a class=\"external text\" href=\"http:\/\/worldcat.org\/issn\/0955-0674\" rel=\"nofollow\">0955-0674<\/a>.<\/span><\/span><\/li>\n<li id=\"cite_note-13\"><span class=\"mw-cite-backlink\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_ref-13\"><span class=\"cite-accessibility-label\">\u0386\u03bb\u03bc\u03b1 \u03c0\u03ac\u03bd\u03c9<\/span>\u2191<\/a><\/span>\u00a0<span class=\"reference-text\"><span class=\"citation Journal\">Stroh, Christopher; 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J\u00e4nicke, R U; Schulze-Osthoff, K (2003-01).\u00a0<a class=\"external text\" href=\"https:\/\/www.nature.com\/articles\/4401160\" rel=\"nofollow\">\u00abMany cuts to ruin: a comprehensive update of caspase substrates\u00bb<\/a>\u00a0(\u03c3\u03c4\u03b1 \u03b1\u03b3\u03b3\u03bb\u03b9\u03ba\u03ac).\u00a0<i>Cell Death and Differentiation<\/i>\u00a0<b>10<\/b>\u00a0(1): 76\u2013100.\u00a0<a class=\"mw-redirect\" title=\"Digital object identifier\" href=\"https:\/\/el.wikipedia.org\/wiki\/Digital_object_identifier\">doi<\/a>:<span class=\"neverexpand\"><a class=\"external text\" href=\"http:\/\/dx.doi.org\/10.1038%2Fsj.cdd.4401160\" rel=\"nofollow\">10.1038\/sj.cdd.4401160<\/a><\/span>.\u00a0<a title=\"International Standard Serial Number\" href=\"https:\/\/el.wikipedia.org\/wiki\/International_Standard_Serial_Number\">ISSN<\/a>\u00a0<a class=\"external text\" href=\"http:\/\/worldcat.org\/issn\/1350-9047\" rel=\"nofollow\">1350-9047<\/a>.<\/span><\/span><\/li>\n<li id=\"cite_note-15\"><span class=\"mw-cite-backlink\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_ref-15\"><span class=\"cite-accessibility-label\">\u0386\u03bb\u03bc\u03b1 \u03c0\u03ac\u03bd\u03c9<\/span>\u2191<\/a><\/span>\u00a0<span class=\"reference-text\"><span class=\"citation Journal\">Cryns, Vincent; Yuan, Junying (1998-06-01).\u00a0<a class=\"external text\" href=\"http:\/\/genesdev.cshlp.org\/content\/12\/11\/1551\" rel=\"nofollow\">\u00abProteases to die for\u00bb<\/a>\u00a0(\u03c3\u03c4\u03b1 \u03b1\u03b3\u03b3\u03bb\u03b9\u03ba\u03ac).\u00a0<i>Genes &amp; Development<\/i>\u00a0<b>12<\/b>\u00a0(11): 1551\u20131570.\u00a0<a class=\"mw-redirect\" title=\"Digital object identifier\" href=\"https:\/\/el.wikipedia.org\/wiki\/Digital_object_identifier\">doi<\/a>:<span class=\"neverexpand\"><a class=\"external text\" href=\"http:\/\/dx.doi.org\/10.1101%2Fgad.12.11.1551\" rel=\"nofollow\">10.1101\/gad.12.11.1551<\/a><\/span>.\u00a0<a title=\"International Standard Serial Number\" href=\"https:\/\/el.wikipedia.org\/wiki\/International_Standard_Serial_Number\">ISSN<\/a>\u00a0<a class=\"external text\" href=\"http:\/\/worldcat.org\/issn\/0890-9369\" rel=\"nofollow\">0890-9369<\/a>.<\/span><\/span><\/li>\n<li id=\"cite_note-16\"><span class=\"mw-cite-backlink\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_ref-16\"><span class=\"cite-accessibility-label\">\u0386\u03bb\u03bc\u03b1 \u03c0\u03ac\u03bd\u03c9<\/span>\u2191<\/a><\/span>\u00a0<span class=\"reference-text\"><span class=\"citation Journal\">G\u00f6hring, F; Schwab, B L; Nicotera, P; Leist, M; Fackelmayer, F O (1997-12-15).\u00a0<a class=\"external text\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1170336\/\" rel=\"nofollow\">\u00abThe novel SAR-binding domain of scaffold attachment factor A (SAF-A) is a target in apoptotic nuclear breakdown.\u00bb<\/a>.\u00a0<i>The EMBO Journal<\/i>\u00a0<b>16<\/b>\u00a0(24): 7361\u20137371.\u00a0<a class=\"mw-redirect\" title=\"Digital object identifier\" href=\"https:\/\/el.wikipedia.org\/wiki\/Digital_object_identifier\">doi<\/a>:<span class=\"neverexpand\"><a class=\"external text\" href=\"http:\/\/dx.doi.org\/10.1093%2Femboj%2F16.24.7361\" rel=\"nofollow\">10.1093\/emboj\/16.24.7361<\/a><\/span>.\u00a0<a title=\"International Standard Serial Number\" href=\"https:\/\/el.wikipedia.org\/wiki\/International_Standard_Serial_Number\">ISSN<\/a>\u00a0<a class=\"external text\" href=\"http:\/\/worldcat.org\/issn\/0261-4189\" rel=\"nofollow\">0261-4189<\/a>.\u00a0<a title=\"PubMed Identifier\" href=\"https:\/\/el.wikipedia.org\/wiki\/PubMed_Identifier\">PMID<\/a>\u00a0<a class=\"external text\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9405365\" rel=\"nofollow\">9405365<\/a>.\u00a0<a title=\"PubMed Central\" href=\"https:\/\/el.wikipedia.org\/wiki\/PubMed_Central\">PMC<\/a><a class=\"external text\" href=\"http:\/\/www.pubmedcentral.nih.gov\/articlerender.fcgi?tool=pmcentrez&amp;artid=PMC1170336\" rel=\"nofollow\">PMC1170336<\/a>.<\/span><\/span><\/li>\n<li id=\"cite_note-17\"><span class=\"mw-cite-backlink\"><a href=\"https:\/\/el.wikipedia.org\/wiki\/%CE%9A%CE%B1%CF%83%CF%80%CE%AC%CF%83%CE%B5%CF%82#cite_ref-17\"><span class=\"cite-accessibility-label\">\u0386\u03bb\u03bc\u03b1 \u03c0\u03ac\u03bd\u03c9<\/span>\u2191<\/a><\/span>\u00a0<span class=\"reference-text\"><span class=\"citation web\">\u03a1\u03bf\u03cd\u03ba\u03bf\u03c2, \u0392\u03b1\u03c3\u03af\u03bb\u03b5\u03b9\u03bf\u03c2 (2008). [file:\/\/\/C:\/Users\/&#8217;\/Downloads\/Vassilis_Roukos_phD_2008.pdf \u00ab\u0394\u03b9\u03b4\u03b1\u03ba\u03c4\u03bf\u03c1\u03b9\u03ba\u03ae \u0394\u03b9\u03b1\u03c4\u03c1\u03b9\u03b2\u03ae\u00bb].\u00a0<i>\u03a0\u03b1\u03bd\u03b5\u03c0\u03b9\u03c3\u03c4\u03ae\u03bc\u03b9\u03bf \u03a0\u03b1\u03c4\u03c1\u03ce\u03bd<\/i>. \u03c0\u03b1\u03bd\u03b5\u03c0\u03b9\u03c3\u03c4\u03ae\u03bc\u03b9\u03bf \u03a0\u03b1\u03c4\u03c1\u03ce\u03bd<span class=\"reference-accessdate\">. \u0391\u03bd\u03b1\u03ba\u03c4\u03ae\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03b9\u03c2 2018-5-12<\/span>.<\/span><\/span><\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"bodyContent\" class=\"mw-body-content\">\n<div id=\"siteSub\" class=\"noprint\"><\/div>\n<div id=\"contentSub\" class=\"\"><\/div>\n<div id=\"jump-to-nav\" class=\"mw-jump\"><\/div>\n<div id=\"mw-content-text\" class=\"mw-content-ltr ve-init-mw-desktopArticleTarget-editableContent\" dir=\"ltr\" lang=\"el\">\n<div class=\"mw-parser-output\">\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u03a3\u03c4\u03b1 \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03b1 \u03c4\u03bf\u03c5 \u03bc\u03b1\u03b8\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 &#8220;\u0395\u03ba\u03c0\u03b1\u03b9\u03b4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03a4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1- \u03a0\u03bf\u03bb\u03c5\u03bc\u03ad\u03c3\u03b1 \u03c3\u03c4\u03b7 \u0394\u03b9\u03b4\u03b1\u03c3\u03ba\u03b1\u03bb\u03af\u03b1 \u03c4\u03b7\u03c2 \u0392\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2\u00a0 \u00a0\u03c4\u03bf\u03c5 \u03bc\u03b5\u03c4\u03b1\u03c0\u03c4\u03c5\u03c7\u03b9\u03b1\u03ba\u03bf\u03cd \u03c0\u03c1\u03bf\u03b3\u03c1\u03ac\u03bc\u03bc\u03b1\u03c4\u03bf\u03c2 \u00a8\u0394\u03b9\u03b4\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03c4\u03b7\u03c2 \u0392\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2&#8221;, \u03ba\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03ba\u03b1\u03b8\u03bf\u03b4\u03ae\u03b3\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u0394\u03ac\u03c3\u03ba\u03b1\u03bb\u03bf\u03c5 (\u039caster of the Universe) \u03a0. \u03a3\u03c4\u03b1\u03c3\u03b9\u03bd\u03ac\u03ba\u03b7, \u03ad\u03c6\u03c4\u03b9\u03b1\u03be\u03b1&#8230;<\/p>\n","protected":false},"author":24,"featured_media":635,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[39],"tags":[40],"class_list":["post-634","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-39","tag-40"],"_links":{"self":[{"href":"https:\/\/mde.biologia.gr\/koupa\/wp-json\/wp\/v2\/posts\/634","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mde.biologia.gr\/koupa\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mde.biologia.gr\/koupa\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mde.biologia.gr\/koupa\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/mde.biologia.gr\/koupa\/wp-json\/wp\/v2\/comments?post=634"}],"version-history":[{"count":10,"href":"https:\/\/mde.biologia.gr\/koupa\/wp-json\/wp\/v2\/posts\/634\/revisions"}],"predecessor-version":[{"id":648,"href":"https:\/\/mde.biologia.gr\/koupa\/wp-json\/wp\/v2\/posts\/634\/revisions\/648"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mde.biologia.gr\/koupa\/wp-json\/wp\/v2\/media\/635"}],"wp:attachment":[{"href":"https:\/\/mde.biologia.gr\/koupa\/wp-json\/wp\/v2\/media?parent=634"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mde.biologia.gr\/koupa\/wp-json\/wp\/v2\/categories?post=634"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mde.biologia.gr\/koupa\/wp-json\/wp\/v2\/tags?post=634"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}